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- W2095122080 abstract "The effects of Hypericum perforatum L. (Hypericaceae) crude ethanol extract (A), ethyl acetate extract (B), aqueous extract (C) and infusion (I), on pentobarbital induced sleeping time, intestinal motility, and their analgesic activity, have been investigated. Extracts A and B exhibited significant stimulatory and antidepressant effects on the CNS. Both extracts prolonged sleep, increasing time up to more than 25 min. The antidepressive activity of extract A was also achieved by significant reduction of the myorelaxant activity of diazepam. Extract B exhibited strong analgesic activity reducing abdominal stretching induced by acetic acid by nearly 50 %. Extracts A, B and C exhibited spasmolytic activity, significantly reducing intestine motility." @default.
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- W2095122080 date "2000-12-01" @default.
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- W2095122080 title "Pharmacodynamic study of Hypericum perforatum L." @default.
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- W2095122080 doi "https://doi.org/10.1016/s0944-7113(00)80027-6" @default.
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