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• W2095163141 abstract "The effect of subcutaneous naloxone administration on the consumption of a weak ethanol solution in rats on the three consecutive days (testing days) was investigated using a behavioral paradigm which includes a first forced ethanol exposure (conditioning day) followed by a two-bottle ethanol/water choice procedure. Besides reducing fluid intake, naloxone treatment prior to forced ethanol exposure interferes with the acquisition of ethanol preference. Post-conditioning naloxone administration fails to affect ethanol preference. Administration of naloxone prior to the first testing session induces a reduction on total fluid intake, at the day of treatment; a decrease on ethanol preference throughout the three consecutive testing days is also observed with the higher dose of the antagonist (5 mg/kg). An involvement of endogenous opioids in ethanol consumption is suggested through the modulation of alcohol reinforcement or the affective quality of the gustatory cue." @default.
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• W2095163141 date "1988-01-01" @default.
• W2095163141 modified "2023-09-26" @default.
• W2095163141 title "Naloxone decreases ethanol consumption within a free choice paradigm in rats" @default.
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• W2095163141 doi "https://doi.org/10.1016/0091-3057(88)90270-5" @default.
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