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• W2095177974 endingPage "1781" @default.
• W2095177974 startingPage "1759" @default.
• W2095177974 abstract "Immunology often conveys the image of large molecules, either in the soluble state or in the membrane of leukocytes, forming multiple contacts with a target for actions of the immune system. Avidity names the ability of a polyvalent molecule to form multiple connections of the same kind with ligands tethered to the same surface. Polyvalent interactions are vastly stronger than their monovalent equivalent. In the present review, the functional consequences of polyvalent interactions are explored in a perspective of recent theoretical advances in understanding the thermodynamics of such binding. From insights on the structural biology of soluble pattern recognition molecules as well as adhesion molecules in the cell membranes or in their proteolytically shed form, this review documents the prominent role of polyvalent interactions in making the immune system a formidable barrier to microbial infection as well as constituting a significant challenge to the application of nanomedicines." @default.
• W2095177974 created "2016-06-24" @default.
• W2095177974 creator A5073210561 @default.
• W2095177974 date "2012-12-01" @default.
• W2095177974 modified "2023-09-26" @default.
• W2095177974 title "On the roles of polyvalent binding in immune recognition: Perspectives in the nanoscience of immunology and the immune response to nanomedicines" @default.
• W2095177974 cites W1490451576 @default.
• W2095177974 cites W1492260064 @default.
• W2095177974 cites W1535906610 @default.
• W2095177974 cites W1540927271 @default.
• W2095177974 cites W1550140963 @default.
• W2095177974 cites W1576773659 @default.
• W2095177974 cites W1596022285 @default.
• W2095177974 cites W1602933202 @default.
• W2095177974 cites W1606312542 @default.
• W2095177974 cites W1607729794 @default.
• W2095177974 cites W1628621684 @default.
• W2095177974 cites W1677439338 @default.
• W2095177974 cites W1786523947 @default.
• W2095177974 cites W1827903646 @default.
• W2095177974 cites W1837680741 @default.
• W2095177974 cites W1851178706 @default.
• W2095177974 cites W185967122 @default.
• W2095177974 cites W1897580483 @default.
• W2095177974 cites W1907115210 @default.
• W2095177974 cites W1936444303 @default.
• W2095177974 cites W1950008523 @default.
• W2095177974 cites W1964343287 @default.
• W2095177974 cites W1966218455 @default.
• W2095177974 cites W1966286149 @default.
• W2095177974 cites W1967076927 @default.
• W2095177974 cites W1968690892 @default.
• W2095177974 cites W1970483666 @default.
• W2095177974 cites W1971255742 @default.
• W2095177974 cites W1972300275 @default.
• W2095177974 cites W1972470306 @default.
• W2095177974 cites W1973666722 @default.
• W2095177974 cites W1973800056 @default.
• W2095177974 cites W1974717461 @default.
• W2095177974 cites W1975352555 @default.
• W2095177974 cites W1977590404 @default.
• W2095177974 cites W1978018134 @default.
• W2095177974 cites W1978786706 @default.
• W2095177974 cites W1979051703 @default.
• W2095177974 cites W1979286662 @default.
• W2095177974 cites W1979639615 @default.
• W2095177974 cites W1980609474 @default.
• W2095177974 cites W1981571305 @default.
• W2095177974 cites W1982224775 @default.
• W2095177974 cites W1983009247 @default.
• W2095177974 cites W1983651055 @default.
• W2095177974 cites W1984219496 @default.
• W2095177974 cites W1984464853 @default.
• W2095177974 cites W1986267622 @default.
• W2095177974 cites W1988536357 @default.
• W2095177974 cites W1988952956 @default.
• W2095177974 cites W1988990960 @default.
• W2095177974 cites W1989702202 @default.
• W2095177974 cites W1990643927 @default.
• W2095177974 cites W1990784311 @default.
• W2095177974 cites W1991068964 @default.
• W2095177974 cites W1991672285 @default.
• W2095177974 cites W1993511481 @default.
• W2095177974 cites W1996880045 @default.
• W2095177974 cites W1998206113 @default.
• W2095177974 cites W1998800095 @default.
• W2095177974 cites W1999390565 @default.
• W2095177974 cites W2000263240 @default.
• W2095177974 cites W2002040632 @default.
• W2095177974 cites W2002445925 @default.
• W2095177974 cites W2002636083 @default.
• W2095177974 cites W2003111769 @default.
• W2095177974 cites W2004273103 @default.
• W2095177974 cites W2006245117 @default.
• W2095177974 cites W2006657990 @default.
• W2095177974 cites W2006712680 @default.
• W2095177974 cites W2007172083 @default.
• W2095177974 cites W2007272508 @default.
• W2095177974 cites W2007408185 @default.
• W2095177974 cites W2007700411 @default.
• W2095177974 cites W2008635331 @default.
• W2095177974 cites W2008869933 @default.
• W2095177974 cites W2009611610 @default.
• W2095177974 cites W2011500156 @default.
• W2095177974 cites W2013379647 @default.
• W2095177974 cites W2013417615 @default.
• W2095177974 cites W2014671098 @default.
• W2095177974 cites W2015326650 @default.
• W2095177974 cites W2015826818 @default.
• W2095177974 cites W2015831421 @default.
• W2095177974 cites W2016011680 @default.
• W2095177974 cites W2019137678 @default.
• W2095177974 cites W2020024962 @default.
• W2095177974 cites W2020723775 @default.
• W2095177974 cites W2021074141 @default.
• W2095177974 cites W2021221687 @default.
• W2095177974 cites W2021502161 @default.
• W2095177974 cites W2021755139 @default.

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