FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095193895> ?p ?o ?g. }

• W2095193895 endingPage "n/a" @default.
• W2095193895 startingPage "n/a" @default.
• W2095193895 abstract "The use of bioactive microspheres as bone filling materials has received much attention due to their ability to fill the bone defects with irregular and complex shapes and sizes. Divalent Mg(2+) modified silicate-based diopside (DIOP: CaMgSi(2)O(6)) and tetravalent Zr(4+) modified silicate-based baghdadite (BAGD: Ca(3)ZrSi(2)O(9)) ceramics have shown excellent in vitro bioactivity for potential bone repair application. However, their in vivo osteogenesis has not been systematically investigated. The aim of this study is to prepare DIOP and BAGD ceramic microspheres and investigate their in vivo osteogenesis. DIOP and BAGD ceramic spheres with loose microstructure were successfully prepared. The dissolution ability of two silicate-based bioceramics was investigated by testing the release of SiO 44- ions after soaking them in phosphate buffered saline. The ceramic spheres were implanted into supracondylar site of the femur defects in Wistar rats and the degree of in vivo osteogenesis was evaluated by hematoxylin and eosin (H and E), Safranin O staining, tartrate-resistant acid phosphatase (TRAP) staining, and immunohistochemistry (type I collagen: Col I, osteopontin: OPN) analyses. The results have shown that BAGD spheres induced a higher rate of new bone formation in the defects than did DIOP and β-tricalcium phosphate (β-TCP) spheres. Immunohistochemical analysis showed greater expression of Col I and OPN in BAGD group compared to DIOP and β-TCP groups. The study indicates different ion modification playing an important role to regulate the in vivo osteogenesis of silicate-based bioceramics. BAGD spheres are a promising bone filler material due to their significantly enhanced osteogenesis, compared to β-TCP spheres." @default.
• W2095193895 created "2016-06-24" @default.
• W2095193895 creator A5001153538 @default.
• W2095193895 creator A5055092165 @default.
• W2095193895 creator A5087744772 @default.
• W2095193895 date "2012-01-01" @default.
• W2095193895 modified "2023-09-28" @default.
• W2095193895 title "The in vivo osteogenesis of Mg or Zr-modified silicate-based bioceramic spheres" @default.
• W2095193895 cites W113956530 @default.
• W2095193895 cites W1541935925 @default.
• W2095193895 cites W1965696823 @default.
• W2095193895 cites W1966118797 @default.
• W2095193895 cites W1970802613 @default.
• W2095193895 cites W1974825501 @default.
• W2095193895 cites W1980241688 @default.
• W2095193895 cites W1987495583 @default.
• W2095193895 cites W2002246983 @default.
• W2095193895 cites W2003413019 @default.
• W2095193895 cites W2005124394 @default.
• W2095193895 cites W2007566603 @default.
• W2095193895 cites W2013979944 @default.
• W2095193895 cites W2015547514 @default.
• W2095193895 cites W2025703295 @default.
• W2095193895 cites W2026533844 @default.
• W2095193895 cites W2030933445 @default.
• W2095193895 cites W2033205456 @default.
• W2095193895 cites W2036669971 @default.
• W2095193895 cites W2038381261 @default.
• W2095193895 cites W2043310171 @default.
• W2095193895 cites W2044316388 @default.
• W2095193895 cites W2061489090 @default.
• W2095193895 cites W2062624513 @default.
• W2095193895 cites W2066043435 @default.
• W2095193895 cites W2066430204 @default.
• W2095193895 cites W2070733566 @default.
• W2095193895 cites W2074789571 @default.
• W2095193895 cites W2086608828 @default.
• W2095193895 cites W2105273891 @default.
• W2095193895 cites W2115726067 @default.
• W2095193895 cites W2128093007 @default.
• W2095193895 cites W2143195935 @default.
• W2095193895 cites W2208935832 @default.
• W2095193895 cites W4244993123 @default.
• W2095193895 doi "https://doi.org/10.1002/jbm.a.34161" @default.
• W2095193895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22499392" @default.
• W2095193895 hasPublicationYear "2012" @default.
• W2095193895 type Work @default.
• W2095193895 sameAs 2095193895 @default.
• W2095193895 citedByCount "12" @default.
• W2095193895 countsByYear W20951938952014 @default.
• W2095193895 countsByYear W20951938952015 @default.
• W2095193895 countsByYear W20951938952017 @default.
• W2095193895 countsByYear W20951938952018 @default.
• W2095193895 countsByYear W20951938952019 @default.
• W2095193895 countsByYear W20951938952020 @default.
• W2095193895 countsByYear W20951938952022 @default.
• W2095193895 countsByYear W20951938952023 @default.
• W2095193895 crossrefType "journal-article" @default.
• W2095193895 hasAuthorship W2095193895A5001153538 @default.
• W2095193895 hasAuthorship W2095193895A5055092165 @default.
• W2095193895 hasAuthorship W2095193895A5087744772 @default.
• W2095193895 hasConcept C126322002 @default.
• W2095193895 hasConcept C127413603 @default.
• W2095193895 hasConcept C136229726 @default.
• W2095193895 hasConcept C150903083 @default.
• W2095193895 hasConcept C159985019 @default.
• W2095193895 hasConcept C192562407 @default.
• W2095193895 hasConcept C207001950 @default.
• W2095193895 hasConcept C2777335606 @default.
• W2095193895 hasConcept C2780300285 @default.
• W2095193895 hasConcept C2780804394 @default.
• W2095193895 hasConcept C2781201070 @default.
• W2095193895 hasConcept C42360764 @default.
• W2095193895 hasConcept C71924100 @default.
• W2095193895 hasConcept C86803240 @default.
• W2095193895 hasConceptScore W2095193895C126322002 @default.
• W2095193895 hasConceptScore W2095193895C127413603 @default.
• W2095193895 hasConceptScore W2095193895C136229726 @default.
• W2095193895 hasConceptScore W2095193895C150903083 @default.
• W2095193895 hasConceptScore W2095193895C159985019 @default.
• W2095193895 hasConceptScore W2095193895C192562407 @default.
• W2095193895 hasConceptScore W2095193895C207001950 @default.
• W2095193895 hasConceptScore W2095193895C2777335606 @default.
• W2095193895 hasConceptScore W2095193895C2780300285 @default.
• W2095193895 hasConceptScore W2095193895C2780804394 @default.
• W2095193895 hasConceptScore W2095193895C2781201070 @default.
• W2095193895 hasConceptScore W2095193895C42360764 @default.
• W2095193895 hasConceptScore W2095193895C71924100 @default.
• W2095193895 hasConceptScore W2095193895C86803240 @default.
• W2095193895 hasLocation W20951938951 @default.
• W2095193895 hasLocation W20951938952 @default.
• W2095193895 hasOpenAccess W2095193895 @default.
• W2095193895 hasPrimaryLocation W20951938951 @default.
• W2095193895 hasRelatedWork W1192246387 @default.
• W2095193895 hasRelatedWork W1993510250 @default.
• W2095193895 hasRelatedWork W2809145417 @default.
• W2095193895 hasRelatedWork W2886518506 @default.
• W2095193895 hasRelatedWork W2990587676 @default.

• next