Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095242525> ?p ?o ?g. }
- W2095242525 endingPage "425" @default.
- W2095242525 startingPage "419" @default.
- W2095242525 abstract "The objective of this study was to investigate early changes in oxygenation by means of the multiple inert gas elimination technique and in coagulation by means of thromboelastography (TEG) after right-sided pulmonary contusion (PC) in swine. Anesthetized swine (group 1; n = 8) sustained a right-chest PC by a captive-bolt stunner. Multiple inert gas elimination technique, TEG, and thoracic computed tomography (CT) scans were performed before and 10, 30, 60, and 120 min after injury. Three-dimensional CT scan reconstruction enabled measurement of volumes of poorly (Vol(Poor)) and nonaerated (Vol(Non)) lung. Eight animals (group 0) were used as uninjured controls. Pulmonary contusion led to sustained tachycardia and transient hypotension. Partial pressure of arterial oxygen (PaO2) decreased from 83.9 +/- 4.2 mmHg at baseline to 51.3 +/- 2.8 mmHg 10 min after PC (P < 0.001). Vol(Poor) and Vol(Non) on the right increased significantly after PC, followed by gradual progression in injury marked by decreased Vol(Poor) and increased Vol(Non). By the multiple inert gas elimination technique, blood flow to the true shunt compartment increased from 4.4% +/- 1.0% at baseline to 21.2% +/- 4.9% 10 min after PC, P < 0.001, peaked at 33.2% +/- 7.5% 30 min after PC, P < 0.001, and remained significantly higher compared with controls. Transient increase in blood flow to low and very low ventilation-perfusion (V/Q) compartments was also seen. Clot reaction time and formation rate by TEG increased at 2 h after PC. True shunt is the major cause of hypoxemia after PC, but V/Q mismatch also contributes significantly early after injury. By CT, PC leads to significant loss of functional lung volume on the side of injury. A mild hypocoagulable state was identified 2 h after injury." @default.
- W2095242525 created "2016-06-24" @default.
- W2095242525 creator A5003778917 @default.
- W2095242525 creator A5018123383 @default.
- W2095242525 creator A5072229293 @default.
- W2095242525 creator A5076842349 @default.
- W2095242525 creator A5089875347 @default.
- W2095242525 date "2010-04-01" @default.
- W2095242525 modified "2023-09-26" @default.
- W2095242525 title "DYNAMIC CHANGES IN SHUNT AND VENTILATION-PERFUSION MISMATCH FOLLOWING EXPERIMENTAL PULMONARY CONTUSION" @default.
- W2095242525 cites W154118068 @default.
- W2095242525 cites W1879303347 @default.
- W2095242525 cites W1946257617 @default.
- W2095242525 cites W1984418892 @default.
- W2095242525 cites W1987820774 @default.
- W2095242525 cites W1990202497 @default.
- W2095242525 cites W1992034786 @default.
- W2095242525 cites W2022444710 @default.
- W2095242525 cites W2032984955 @default.
- W2095242525 cites W2053490230 @default.
- W2095242525 cites W2061187386 @default.
- W2095242525 cites W2072047475 @default.
- W2095242525 cites W2083140617 @default.
- W2095242525 cites W2115303739 @default.
- W2095242525 cites W2119761195 @default.
- W2095242525 cites W2146526610 @default.
- W2095242525 cites W2175733313 @default.
- W2095242525 cites W2217928373 @default.
- W2095242525 cites W2317659435 @default.
- W2095242525 cites W2597070792 @default.
- W2095242525 doi "https://doi.org/10.1097/shk.0b013e3181b8bcd9" @default.
- W2095242525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20407408" @default.
- W2095242525 hasPublicationYear "2010" @default.
- W2095242525 type Work @default.
- W2095242525 sameAs 2095242525 @default.
- W2095242525 citedByCount "24" @default.
- W2095242525 countsByYear W20952425252012 @default.
- W2095242525 countsByYear W20952425252013 @default.
- W2095242525 countsByYear W20952425252014 @default.
- W2095242525 countsByYear W20952425252015 @default.
- W2095242525 countsByYear W20952425252016 @default.
- W2095242525 countsByYear W20952425252017 @default.
- W2095242525 countsByYear W20952425252018 @default.
- W2095242525 countsByYear W20952425252019 @default.
- W2095242525 countsByYear W20952425252020 @default.
- W2095242525 countsByYear W20952425252021 @default.
- W2095242525 countsByYear W20952425252023 @default.
- W2095242525 crossrefType "journal-article" @default.
- W2095242525 hasAuthorship W2095242525A5003778917 @default.
- W2095242525 hasAuthorship W2095242525A5018123383 @default.
- W2095242525 hasAuthorship W2095242525A5072229293 @default.
- W2095242525 hasAuthorship W2095242525A5076842349 @default.
- W2095242525 hasAuthorship W2095242525A5089875347 @default.
- W2095242525 hasBestOaLocation W20952425251 @default.
- W2095242525 hasConcept C126322002 @default.
- W2095242525 hasConcept C146957229 @default.
- W2095242525 hasConcept C158846371 @default.
- W2095242525 hasConcept C164705383 @default.
- W2095242525 hasConcept C178853913 @default.
- W2095242525 hasConcept C2777714996 @default.
- W2095242525 hasConcept C2779589923 @default.
- W2095242525 hasConcept C2780229392 @default.
- W2095242525 hasConcept C2780968331 @default.
- W2095242525 hasConcept C2989005 @default.
- W2095242525 hasConcept C42219234 @default.
- W2095242525 hasConcept C70289976 @default.
- W2095242525 hasConcept C71924100 @default.
- W2095242525 hasConceptScore W2095242525C126322002 @default.
- W2095242525 hasConceptScore W2095242525C146957229 @default.
- W2095242525 hasConceptScore W2095242525C158846371 @default.
- W2095242525 hasConceptScore W2095242525C164705383 @default.
- W2095242525 hasConceptScore W2095242525C178853913 @default.
- W2095242525 hasConceptScore W2095242525C2777714996 @default.
- W2095242525 hasConceptScore W2095242525C2779589923 @default.
- W2095242525 hasConceptScore W2095242525C2780229392 @default.
- W2095242525 hasConceptScore W2095242525C2780968331 @default.
- W2095242525 hasConceptScore W2095242525C2989005 @default.
- W2095242525 hasConceptScore W2095242525C42219234 @default.
- W2095242525 hasConceptScore W2095242525C70289976 @default.
- W2095242525 hasConceptScore W2095242525C71924100 @default.
- W2095242525 hasIssue "4" @default.
- W2095242525 hasLocation W20952425251 @default.
- W2095242525 hasLocation W20952425252 @default.
- W2095242525 hasLocation W20952425253 @default.
- W2095242525 hasOpenAccess W2095242525 @default.
- W2095242525 hasPrimaryLocation W20952425251 @default.
- W2095242525 hasRelatedWork W2046953758 @default.
- W2095242525 hasRelatedWork W2090202907 @default.
- W2095242525 hasRelatedWork W2102240528 @default.
- W2095242525 hasRelatedWork W2140217260 @default.
- W2095242525 hasRelatedWork W2153923174 @default.
- W2095242525 hasRelatedWork W2154641732 @default.
- W2095242525 hasRelatedWork W2154749109 @default.
- W2095242525 hasRelatedWork W2368091405 @default.
- W2095242525 hasRelatedWork W2883249017 @default.
- W2095242525 hasRelatedWork W3014250429 @default.
- W2095242525 hasVolume "33" @default.
- W2095242525 isParatext "false" @default.