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- W2095247369 abstract "The organization of the endoplasmic reticulum (ER) in the cortex of Xenopus oocytes was investigated during maturation and activation using a green fluorescent protein chimera, immunofluorescence, and electron microscopy. Dense clusters of ER developed on the vegetal side (the side opposite the meiotic spindle) during maturation. Small clusters appeared transiently at the time of nuclear envelope breakdown, disappeared at the time of first polar body formation, and then reappeared as larger clusters in mature eggs. The appearance of the large ER clusters was correlated with an increase in releasability of Ca(2+) by IP(3). The clusters dispersed during the Ca(2+) wave at activation. Possible relationships of ER structure and Ca(2+) regulation are discussed." @default.
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- W2095247369 date "2001-04-01" @default.
- W2095247369 modified "2023-10-15" @default.
- W2095247369 title "Changes in Organization of the Endoplasmic Reticulum during<i>Xenopus</i>Oocyte Maturation and Activation" @default.
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- W2095247369 doi "https://doi.org/10.1091/mbc.12.4.1103" @default.
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