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• W2095247923 startingPage "3" @default.
• W2095247923 abstract "Flaviviruses are small spherical virus particles covered by a dense icosahedral array of envelope (E) proteins that mediate virus attachment to cells and the fusion of viral and cellular membranes. Our understanding of the mechanism by which flavivirus E proteins orchestrate entry into cells has been advanced by studies of E structure and arrangement on the virion at different steps of the virus entry/membrane fusion process. When combined with an increasingly clear (albeit still incomplete) view of the cell biology of virus entry, these advances suggest new antiviral strategies. Indeed, inhibitors that target cellular and viral processes involved in entry show promise as powerful tools to study this critical step of the viral lifecycle, and with luck, may ultimately lead to therapeutic advances." @default.
• W2095247923 created "2016-06-24" @default.
• W2095247923 creator A5047104561 @default.
• W2095247923 creator A5076442194 @default.
• W2095247923 date "2013-02-01" @default.
• W2095247923 modified "2023-09-30" @default.
• W2095247923 title "Flaviviruses: braking the entering" @default.
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• W2095247923 doi "https://doi.org/10.1016/j.coviro.2012.12.001" @default.
• W2095247923 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3601797" @default.
• W2095247923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23352692" @default.
• W2095247923 hasPublicationYear "2013" @default.
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