Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095254689> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2095254689 endingPage "6883" @default.
- W2095254689 startingPage "6882" @default.
- W2095254689 abstract "The remote 5‘-3H V/K kinetic isotope effect (KIE) observed in human thymidine phosphorylase (6.1%) is significantly larger than can be explained by the reaction chemistry. One hypothesis connects the 5‘-3H KIE in purine nucleoside phosphorylase to that enzyme's SN1 transition state. The transition state of thymidine phosphorylase, however, is an SN2 nucleophilic displacement. Here we report equilibrium binding isotope effects sufficiently large to explain the presence of this substantial KIE in thymidine phosphorylase." @default.
- W2095254689 created "2016-06-24" @default.
- W2095254689 creator A5018522950 @default.
- W2095254689 creator A5058998677 @default.
- W2095254689 date "2004-05-15" @default.
- W2095254689 modified "2023-10-16" @default.
- W2095254689 title "Binding Causes the Remote [5‘-<sup>3</sup>H]Thymidine Kinetic Isotope Effect in Human Thymidine Phosphorylase" @default.
- W2095254689 cites W1004640597 @default.
- W2095254689 cites W1041023894 @default.
- W2095254689 cites W1970327093 @default.
- W2095254689 cites W1978347107 @default.
- W2095254689 cites W2027081836 @default.
- W2095254689 cites W2027484071 @default.
- W2095254689 cites W2027928806 @default.
- W2095254689 cites W2028531632 @default.
- W2095254689 cites W2044174046 @default.
- W2095254689 cites W2080632083 @default.
- W2095254689 cites W2094810573 @default.
- W2095254689 cites W2099841293 @default.
- W2095254689 cites W2130327573 @default.
- W2095254689 cites W2165138879 @default.
- W2095254689 cites W2167062658 @default.
- W2095254689 cites W2612574275 @default.
- W2095254689 doi "https://doi.org/10.1021/ja0492642" @default.
- W2095254689 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15174854" @default.
- W2095254689 hasPublicationYear "2004" @default.
- W2095254689 type Work @default.
- W2095254689 sameAs 2095254689 @default.
- W2095254689 citedByCount "24" @default.
- W2095254689 countsByYear W20952546892012 @default.
- W2095254689 countsByYear W20952546892013 @default.
- W2095254689 countsByYear W20952546892014 @default.
- W2095254689 countsByYear W20952546892015 @default.
- W2095254689 countsByYear W20952546892017 @default.
- W2095254689 crossrefType "journal-article" @default.
- W2095254689 hasAuthorship W2095254689A5018522950 @default.
- W2095254689 hasAuthorship W2095254689A5058998677 @default.
- W2095254689 hasConcept C104317684 @default.
- W2095254689 hasConcept C121332964 @default.
- W2095254689 hasConcept C164304813 @default.
- W2095254689 hasConcept C181199279 @default.
- W2095254689 hasConcept C184779094 @default.
- W2095254689 hasConcept C185592680 @default.
- W2095254689 hasConcept C194101687 @default.
- W2095254689 hasConcept C204779464 @default.
- W2095254689 hasConcept C2776476023 @default.
- W2095254689 hasConcept C2776735402 @default.
- W2095254689 hasConcept C2777108182 @default.
- W2095254689 hasConcept C512185932 @default.
- W2095254689 hasConcept C552990157 @default.
- W2095254689 hasConcept C55493867 @default.
- W2095254689 hasConcept C58364064 @default.
- W2095254689 hasConcept C62520636 @default.
- W2095254689 hasConcept C69928629 @default.
- W2095254689 hasConcept C71240020 @default.
- W2095254689 hasConcept C71615608 @default.
- W2095254689 hasConcept C96765332 @default.
- W2095254689 hasConceptScore W2095254689C104317684 @default.
- W2095254689 hasConceptScore W2095254689C121332964 @default.
- W2095254689 hasConceptScore W2095254689C164304813 @default.
- W2095254689 hasConceptScore W2095254689C181199279 @default.
- W2095254689 hasConceptScore W2095254689C184779094 @default.
- W2095254689 hasConceptScore W2095254689C185592680 @default.
- W2095254689 hasConceptScore W2095254689C194101687 @default.
- W2095254689 hasConceptScore W2095254689C204779464 @default.
- W2095254689 hasConceptScore W2095254689C2776476023 @default.
- W2095254689 hasConceptScore W2095254689C2776735402 @default.
- W2095254689 hasConceptScore W2095254689C2777108182 @default.
- W2095254689 hasConceptScore W2095254689C512185932 @default.
- W2095254689 hasConceptScore W2095254689C552990157 @default.
- W2095254689 hasConceptScore W2095254689C55493867 @default.
- W2095254689 hasConceptScore W2095254689C58364064 @default.
- W2095254689 hasConceptScore W2095254689C62520636 @default.
- W2095254689 hasConceptScore W2095254689C69928629 @default.
- W2095254689 hasConceptScore W2095254689C71240020 @default.
- W2095254689 hasConceptScore W2095254689C71615608 @default.
- W2095254689 hasConceptScore W2095254689C96765332 @default.
- W2095254689 hasIssue "22" @default.
- W2095254689 hasLocation W20952546891 @default.
- W2095254689 hasLocation W20952546892 @default.
- W2095254689 hasOpenAccess W2095254689 @default.
- W2095254689 hasPrimaryLocation W20952546891 @default.
- W2095254689 hasRelatedWork W1621443637 @default.
- W2095254689 hasRelatedWork W1816015458 @default.
- W2095254689 hasRelatedWork W1974384202 @default.
- W2095254689 hasRelatedWork W2040680298 @default.
- W2095254689 hasRelatedWork W2049570269 @default.
- W2095254689 hasRelatedWork W2069844990 @default.
- W2095254689 hasRelatedWork W2072400918 @default.
- W2095254689 hasRelatedWork W2095254689 @default.
- W2095254689 hasRelatedWork W2232837419 @default.
- W2095254689 hasRelatedWork W50650903 @default.
- W2095254689 hasVolume "126" @default.
- W2095254689 isParatext "false" @default.
- W2095254689 isRetracted "false" @default.
- W2095254689 magId "2095254689" @default.
- W2095254689 workType "article" @default.