Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095258151> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2095258151 endingPage "209a" @default.
- W2095258151 startingPage "209a" @default.
- W2095258151 abstract "The role of different types of interactions and their contribution in the stabilization of bovine α-lactalbumin (α-LA) molten globule in presence of cationic surfactant, hexadecyl trimethyl ammonium bromide (HTAB) and anionic surfactant, sodium dodecyl sulphate (SDS) have been examined using a combination of spectroscopic, light scattering and calorimetric techniques. At lower concentration of the surfactants, the thermodynamic parameters obtained from UV-Visible spectroscopy suggested an increased exposure of non-polar groups in HTAB while a possible restructuring of non-polar groups were indicated in SDS. The fluorescence and circular dichroism spectroscopy showed the formation of an intermediate state at various concentrations in presence of HTAB and SDS while the lifetime measurements supported the assumption of protein-surfactant complex stability in HTAB as compared to SDS. The hydrodynamic diameter and ζ-potential were analyzed by dynamic light scattering (DLS) which also implicated the combined influence of electrostatic and hydrophobic interactions in α-LA unfolding in HTAB and only hydrophobic interactions in SDS. The binding parameters for ANS obtained from isothermal titration calorimetric (ITC) measurements suggested a high stability of α-LA molten globule and the role of enthalpic and entropic contribution in the binding of ANS in HTAB. It also indicated the fragility of α-LA molten globule in SDS. The possible binding sites as well as the interactions of ANS with the molten globule were also investigated from the thermodynamic parameters obtained from ITC. We, thus propose that the molten globule state obtained in HTAB and SDS are very different from one another as well as the conventional molten globule state of α-LA obtained in presence of chemical denaturants." @default.
- W2095258151 created "2016-06-24" @default.
- W2095258151 creator A5056917493 @default.
- W2095258151 creator A5081349312 @default.
- W2095258151 date "2011-02-01" @default.
- W2095258151 modified "2023-09-30" @default.
- W2095258151 title "A comprehensive Analysis of Bovine αα-Lactalbumin Molten Globule in Presence of Surfactants: Biophysical Correlates" @default.
- W2095258151 doi "https://doi.org/10.1016/j.bpj.2010.12.1352" @default.
- W2095258151 hasPublicationYear "2011" @default.
- W2095258151 type Work @default.
- W2095258151 sameAs 2095258151 @default.
- W2095258151 citedByCount "0" @default.
- W2095258151 crossrefType "journal-article" @default.
- W2095258151 hasAuthorship W2095258151A5056917493 @default.
- W2095258151 hasAuthorship W2095258151A5081349312 @default.
- W2095258151 hasBestOaLocation W20952581511 @default.
- W2095258151 hasConcept C118493188 @default.
- W2095258151 hasConcept C127413603 @default.
- W2095258151 hasConcept C133571119 @default.
- W2095258151 hasConcept C13965031 @default.
- W2095258151 hasConcept C14631669 @default.
- W2095258151 hasConcept C155672457 @default.
- W2095258151 hasConcept C179104552 @default.
- W2095258151 hasConcept C184866935 @default.
- W2095258151 hasConcept C185592680 @default.
- W2095258151 hasConcept C2776923230 @default.
- W2095258151 hasConcept C42360764 @default.
- W2095258151 hasConcept C43617362 @default.
- W2095258151 hasConcept C55493867 @default.
- W2095258151 hasConcept C58226133 @default.
- W2095258151 hasConcept C8010536 @default.
- W2095258151 hasConceptScore W2095258151C118493188 @default.
- W2095258151 hasConceptScore W2095258151C127413603 @default.
- W2095258151 hasConceptScore W2095258151C133571119 @default.
- W2095258151 hasConceptScore W2095258151C13965031 @default.
- W2095258151 hasConceptScore W2095258151C14631669 @default.
- W2095258151 hasConceptScore W2095258151C155672457 @default.
- W2095258151 hasConceptScore W2095258151C179104552 @default.
- W2095258151 hasConceptScore W2095258151C184866935 @default.
- W2095258151 hasConceptScore W2095258151C185592680 @default.
- W2095258151 hasConceptScore W2095258151C2776923230 @default.
- W2095258151 hasConceptScore W2095258151C42360764 @default.
- W2095258151 hasConceptScore W2095258151C43617362 @default.
- W2095258151 hasConceptScore W2095258151C55493867 @default.
- W2095258151 hasConceptScore W2095258151C58226133 @default.
- W2095258151 hasConceptScore W2095258151C8010536 @default.
- W2095258151 hasIssue "3" @default.
- W2095258151 hasLocation W20952581511 @default.
- W2095258151 hasOpenAccess W2095258151 @default.
- W2095258151 hasPrimaryLocation W20952581511 @default.
- W2095258151 hasRelatedWork W1967723529 @default.
- W2095258151 hasRelatedWork W1976800050 @default.
- W2095258151 hasRelatedWork W1989098471 @default.
- W2095258151 hasRelatedWork W2013908083 @default.
- W2095258151 hasRelatedWork W2034381166 @default.
- W2095258151 hasRelatedWork W2057183688 @default.
- W2095258151 hasRelatedWork W2089244998 @default.
- W2095258151 hasRelatedWork W2095258151 @default.
- W2095258151 hasRelatedWork W2279427756 @default.
- W2095258151 hasRelatedWork W2698685833 @default.
- W2095258151 hasVolume "100" @default.
- W2095258151 isParatext "false" @default.
- W2095258151 isRetracted "false" @default.
- W2095258151 magId "2095258151" @default.
- W2095258151 workType "article" @default.