Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095280437> ?p ?o ?g. }
- W2095280437 endingPage "670" @default.
- W2095280437 startingPage "668" @default.
- W2095280437 abstract "Cancer/testis-antigens (CTA), a novel and expanding family of immunogenic proteins detected by serological screening of recombinant cDNA expression libraries, encompass promising candidate targets for T-cell based immunotherapy. We screened kryo-preserved tissue of cutaneous T cell lymphoma (CTCL, n=36) such as mycosis fungoides (MF, n=17), pleomorphic cutaneous T-cell lymphoma (n=8) and Sezary's syndrome (SS, n= 11) as well as a non-malignant entity (small plaques parapsoriasis, SPP, n=5), for the expression of CTA by RT-PCR and Northern blot hybridization. From a panel of eleven CTA (MAGE-1, MAGE-C1, MAGE-3, BAGE, GAGE, SSX-1, SSX-2, SSX4, SCP-1, NY-ESO-1 and TS85) (HOM-Tes-85), mRNA expression could be detected for SCP-1 in 8/17 MF and 6/8 pleomorphic CTCL patients but was completely absent in small plaques parapsoriasis. SS patients had a more heterogeneous antigen expression pattern: Gage (1/11), MAGE-1 (3/11), MAGE-3 (6/11), MAGE-C1 (5/11), NY-ESO-1 (7/11) and TS85 (5/11), with expression of MAGE-3 confirmed by immunohistochemistry. CTA could provide defined targets for antigen-based vaccination in a high percentage of cases with CTCL. SCP-1 might serve as an additional diagnostic indicator in early and clinically indistinct lesions suspicious for cutaneous T-cell lymphoma." @default.
- W2095280437 created "2016-06-24" @default.
- W2095280437 creator A5004376273 @default.
- W2095280437 creator A5010896178 @default.
- W2095280437 creator A5034983939 @default.
- W2095280437 creator A5039689921 @default.
- W2095280437 creator A5052989002 @default.
- W2095280437 creator A5055887175 @default.
- W2095280437 creator A5079488614 @default.
- W2095280437 date "2001-10-30" @default.
- W2095280437 modified "2023-10-17" @default.
- W2095280437 title "Expression of cancer/testis antigens in cutaneous T cell lymphomas" @default.
- W2095280437 cites W1976342263 @default.
- W2095280437 cites W1981584846 @default.
- W2095280437 cites W1988679162 @default.
- W2095280437 cites W2000130466 @default.
- W2095280437 cites W2007353300 @default.
- W2095280437 cites W2007749743 @default.
- W2095280437 cites W2014122529 @default.
- W2095280437 cites W2036392773 @default.
- W2095280437 cites W2044230490 @default.
- W2095280437 cites W2044770358 @default.
- W2095280437 cites W2045293238 @default.
- W2095280437 cites W2056947605 @default.
- W2095280437 cites W2066964346 @default.
- W2095280437 cites W2071772278 @default.
- W2095280437 cites W2096385955 @default.
- W2095280437 cites W2104925785 @default.
- W2095280437 cites W2150604820 @default.
- W2095280437 cites W2154977133 @default.
- W2095280437 cites W2405977915 @default.
- W2095280437 cites W3021254998 @default.
- W2095280437 cites W4233406592 @default.
- W2095280437 cites W84939312 @default.
- W2095280437 doi "https://doi.org/10.1002/ijc.1643" @default.
- W2095280437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11807795" @default.
- W2095280437 hasPublicationYear "2001" @default.
- W2095280437 type Work @default.
- W2095280437 sameAs 2095280437 @default.
- W2095280437 citedByCount "33" @default.
- W2095280437 countsByYear W20952804372013 @default.
- W2095280437 countsByYear W20952804372014 @default.
- W2095280437 countsByYear W20952804372022 @default.
- W2095280437 countsByYear W20952804372023 @default.
- W2095280437 crossrefType "journal-article" @default.
- W2095280437 hasAuthorship W2095280437A5004376273 @default.
- W2095280437 hasAuthorship W2095280437A5010896178 @default.
- W2095280437 hasAuthorship W2095280437A5034983939 @default.
- W2095280437 hasAuthorship W2095280437A5039689921 @default.
- W2095280437 hasAuthorship W2095280437A5052989002 @default.
- W2095280437 hasAuthorship W2095280437A5055887175 @default.
- W2095280437 hasAuthorship W2095280437A5079488614 @default.
- W2095280437 hasBestOaLocation W20952804371 @default.
- W2095280437 hasConcept C121608353 @default.
- W2095280437 hasConcept C126322002 @default.
- W2095280437 hasConcept C142724271 @default.
- W2095280437 hasConcept C147483822 @default.
- W2095280437 hasConcept C159654299 @default.
- W2095280437 hasConcept C203014093 @default.
- W2095280437 hasConcept C204232928 @default.
- W2095280437 hasConcept C2776090121 @default.
- W2095280437 hasConcept C2776780870 @default.
- W2095280437 hasConcept C2777701055 @default.
- W2095280437 hasConcept C2777756187 @default.
- W2095280437 hasConcept C2777891184 @default.
- W2095280437 hasConcept C2779338263 @default.
- W2095280437 hasConcept C45189115 @default.
- W2095280437 hasConcept C71924100 @default.
- W2095280437 hasConcept C8891405 @default.
- W2095280437 hasConceptScore W2095280437C121608353 @default.
- W2095280437 hasConceptScore W2095280437C126322002 @default.
- W2095280437 hasConceptScore W2095280437C142724271 @default.
- W2095280437 hasConceptScore W2095280437C147483822 @default.
- W2095280437 hasConceptScore W2095280437C159654299 @default.
- W2095280437 hasConceptScore W2095280437C203014093 @default.
- W2095280437 hasConceptScore W2095280437C204232928 @default.
- W2095280437 hasConceptScore W2095280437C2776090121 @default.
- W2095280437 hasConceptScore W2095280437C2776780870 @default.
- W2095280437 hasConceptScore W2095280437C2777701055 @default.
- W2095280437 hasConceptScore W2095280437C2777756187 @default.
- W2095280437 hasConceptScore W2095280437C2777891184 @default.
- W2095280437 hasConceptScore W2095280437C2779338263 @default.
- W2095280437 hasConceptScore W2095280437C45189115 @default.
- W2095280437 hasConceptScore W2095280437C71924100 @default.
- W2095280437 hasConceptScore W2095280437C8891405 @default.
- W2095280437 hasIssue "5" @default.
- W2095280437 hasLocation W20952804371 @default.
- W2095280437 hasLocation W20952804372 @default.
- W2095280437 hasOpenAccess W2095280437 @default.
- W2095280437 hasPrimaryLocation W20952804371 @default.
- W2095280437 hasRelatedWork W1968386713 @default.
- W2095280437 hasRelatedWork W1982714275 @default.
- W2095280437 hasRelatedWork W2017418416 @default.
- W2095280437 hasRelatedWork W2044770358 @default.
- W2095280437 hasRelatedWork W2124260720 @default.
- W2095280437 hasRelatedWork W2731295483 @default.
- W2095280437 hasRelatedWork W2975546699 @default.
- W2095280437 hasRelatedWork W2976440729 @default.