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• W2095283315 abstract "The design, synthesis and pharmacological evaluation of a novel class of Dmt-Tic dipeptide analogues are described. These resulting analogues bearing different C-terminal functionalities were found to bind to the human δ receptor with high affinity. One specific class of dipeptides bearing urea/thiourea functionalities showed partial to full activation of the δ receptor. Several dipeptides also showed good binding affinities with full activation of the human κ receptor, a novel property for those ligands." @default.
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• W2095283315 date "2001-06-16" @default.
• W2095283315 modified "2023-10-03" @default.
• W2095283315 title "Novel C-Terminus Modifications of the Dmt-Tic Motif: A New Class of Dipeptide Analogues Showing Altered Pharmacological Profiles Toward the Opioid Receptors" @default.
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• W2095283315 doi "https://doi.org/10.1021/jm015532k" @default.
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