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• W2095288465 abstract "Background Sinusitis is a common medical disease with a tremendous economic impact on health care. Our objective was to determine the most cost-effective strategy for the management of acute sinusitis from the societal and payers’ perspectives. Methods A Markov disease simulation model was used for comparing four treatment strategies: (1) no antibiotic (Abx), (2) empiric Abx, (3) CT-based Abx, and (4) clinical guideline-based Abx. Results Empiric Abx treatment was the most cost-effective from the societal perspective. Clinical guideline-based treatment was the most cost-effective strategy from the payers’ perspective ($38,515/quality-adjusted life year). Cost and effectiveness of Abx, time lost from work, and prevalence of acute bacterial sinusitis are influential variables. Conclusion Empiric Abx treatment is a cost-effective strategy from the short-term societal perspective. However, Abx resistance will lead to increased costs and reduced efficacy of this strategy in the long-term. Clinical guidelines provide a low-cost method of targeting therapy." @default.
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• W2095288465 date "2007-07-01" @default.
• W2095288465 modified "2023-10-11" @default.
• W2095288465 title "The Cost-Effectiveness of the Management of Acute Sinusitis" @default.
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• W2095288465 doi "https://doi.org/10.2500/ajr.2007.21.3009" @default.
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