FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095300669> ?p ?o ?g. }

• W2095300669 endingPage "138" @default.
• W2095300669 startingPage "131" @default.
• W2095300669 abstract "In an attempt to improve the physicochemical properties of poorly aqueous soluble ezetimibe, its pharmaceutical co-crystals were successfully engineered with different crystal forming agents; benzoic acid and salicylic acid in equimolar ratios by solution crystallization technique. The physicochemical properties of pure ezetimibe and corresponding co-crystals were accessed in terms of phase solubility studies, melting point, flowability, drug content uniformity, saturation solubility and dissolution studies. Fourier transformation infrared spectroscopy (FTIR), X-ray powder diffractometry (XRPD) and scanning electron microscopy (SEM) techniques were employed to investigate the hydrogen bonding interaction, crystallinity and surface morphological characteristics of prepared co-crystals respectively. The results indicated a marked improvement in flow properties and saturation solubility of co-crystals (p < 0.001). Further, in case of dissolution experiments, both the co-crystals showed a significant enhancement (DE5 and DE20, p < 0.001) in the dissolution profiles as compared to pure ezetimibe. It could be concluded that substantial manipulation of physicochemical properties of ezetimibe could be possible with benzoic acid and salicylic acid using crystal engineering technique." @default.
• W2095300669 created "2016-06-24" @default.
• W2095300669 creator A5024129346 @default.
• W2095300669 creator A5027137258 @default.
• W2095300669 creator A5056133100 @default.
• W2095300669 creator A5065061669 @default.
• W2095300669 creator A5091383246 @default.
• W2095300669 date "2012-05-01" @default.
• W2095300669 modified "2023-09-27" @default.
• W2095300669 title "Improvement in physicochemical properties of ezetimibe using a crystal engineering technique" @default.
• W2095300669 cites W1608460191 @default.
• W2095300669 cites W1967935934 @default.
• W2095300669 cites W1969829161 @default.
• W2095300669 cites W1976544366 @default.
• W2095300669 cites W1977278401 @default.
• W2095300669 cites W1990329196 @default.
• W2095300669 cites W1992255438 @default.
• W2095300669 cites W1997077098 @default.
• W2095300669 cites W2001054843 @default.
• W2095300669 cites W2008894253 @default.
• W2095300669 cites W2013027128 @default.
• W2095300669 cites W2024483780 @default.
• W2095300669 cites W2025155883 @default.
• W2095300669 cites W2038186172 @default.
• W2095300669 cites W2040432233 @default.
• W2095300669 cites W2044594845 @default.
• W2095300669 cites W2056706988 @default.
• W2095300669 cites W2057457198 @default.
• W2095300669 cites W2057816637 @default.
• W2095300669 cites W2063548340 @default.
• W2095300669 cites W2064104154 @default.
• W2095300669 cites W2067129640 @default.
• W2095300669 cites W2070058748 @default.
• W2095300669 cites W2074207007 @default.
• W2095300669 cites W2078886686 @default.
• W2095300669 cites W2093617498 @default.
• W2095300669 cites W2132497207 @default.
• W2095300669 cites W2156285632 @default.
• W2095300669 cites W2157024787 @default.
• W2095300669 cites W2163742089 @default.
• W2095300669 cites W2168728301 @default.
• W2095300669 cites W2417566118 @default.
• W2095300669 cites W4239750817 @default.
• W2095300669 doi "https://doi.org/10.1016/j.powtec.2012.02.020" @default.
• W2095300669 hasPublicationYear "2012" @default.
• W2095300669 type Work @default.
• W2095300669 sameAs 2095300669 @default.
• W2095300669 citedByCount "35" @default.
• W2095300669 countsByYear W20953006692013 @default.
• W2095300669 countsByYear W20953006692014 @default.
• W2095300669 countsByYear W20953006692015 @default.
• W2095300669 countsByYear W20953006692016 @default.
• W2095300669 countsByYear W20953006692017 @default.
• W2095300669 countsByYear W20953006692019 @default.
• W2095300669 countsByYear W20953006692020 @default.
• W2095300669 countsByYear W20953006692021 @default.
• W2095300669 countsByYear W20953006692022 @default.
• W2095300669 countsByYear W20953006692023 @default.
• W2095300669 crossrefType "journal-article" @default.
• W2095300669 hasAuthorship W2095300669A5024129346 @default.
• W2095300669 hasAuthorship W2095300669A5027137258 @default.
• W2095300669 hasAuthorship W2095300669A5056133100 @default.
• W2095300669 hasAuthorship W2095300669A5065061669 @default.
• W2095300669 hasAuthorship W2095300669A5091383246 @default.
• W2095300669 hasConcept C112887158 @default.
• W2095300669 hasConcept C114614502 @default.
• W2095300669 hasConcept C127413603 @default.
• W2095300669 hasConcept C13965031 @default.
• W2095300669 hasConcept C155574463 @default.
• W2095300669 hasConcept C159985019 @default.
• W2095300669 hasConcept C160892712 @default.
• W2095300669 hasConcept C178790620 @default.
• W2095300669 hasConcept C184651966 @default.
• W2095300669 hasConcept C185592680 @default.
• W2095300669 hasConcept C192562407 @default.
• W2095300669 hasConcept C203036418 @default.
• W2095300669 hasConcept C26771246 @default.
• W2095300669 hasConcept C2776839432 @default.
• W2095300669 hasConcept C2778657065 @default.
• W2095300669 hasConcept C2778844314 @default.
• W2095300669 hasConcept C32909587 @default.
• W2095300669 hasConcept C33923547 @default.
• W2095300669 hasConcept C42360764 @default.
• W2095300669 hasConcept C46275449 @default.
• W2095300669 hasConcept C55493867 @default.
• W2095300669 hasConcept C5716244 @default.
• W2095300669 hasConcept C8010536 @default.
• W2095300669 hasConcept C88380143 @default.
• W2095300669 hasConcept C9930424 @default.
• W2095300669 hasConceptScore W2095300669C112887158 @default.
• W2095300669 hasConceptScore W2095300669C114614502 @default.
• W2095300669 hasConceptScore W2095300669C127413603 @default.
• W2095300669 hasConceptScore W2095300669C13965031 @default.
• W2095300669 hasConceptScore W2095300669C155574463 @default.
• W2095300669 hasConceptScore W2095300669C159985019 @default.
• W2095300669 hasConceptScore W2095300669C160892712 @default.
• W2095300669 hasConceptScore W2095300669C178790620 @default.
• W2095300669 hasConceptScore W2095300669C184651966 @default.

• next