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• W2095311937 abstract "Abstract We report on the immunophenotypical characterization of adult human skin transplanted onto severe combined immunodeficienl (SCID) mice. Thirty animals were followed for up to 12 months after receiving split-thickness xenografts. of which 28 were tolerated for the whole test period. Antigen mapping revealed an almost complete preservation of human cellular and extracellular tissue components in long-term trans-plants including skin immune cells (Langerhans-cells, macrophages. lymphocytes) and also parts of the engrafted endolhelium. Hence, xeno-grafts on SCID mice offer a versatile experimental tool for the in vivo study of both human skin immune cell function and endothelial cell-mediated interactions in an environment completely devoid of inter-ferences by adoptive host immune response." @default.
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• W2095311937 date "1993-10-01" @default.
• W2095311937 modified "2023-10-16" @default.
• W2095311937 title "Cellular and molecular composition of human skin in long-term xenografts on SCID mice" @default.
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• W2095311937 doi "https://doi.org/10.1111/j.1600-0625.1993.tb00035.x" @default.
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