FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095349231> ?p ?o ?g. }

• W2095349231 endingPage "735" @default.
• W2095349231 startingPage "730" @default.
• W2095349231 abstract "Abstract— Ultraviolet A (UVA,315–400 nm) radiation is known to be a complete carcinogen, but in contrast to UVB (280-315 nm) radiation, much of the cell damage is oxygen dependent (mediated through reactive oxygen species), and the dominant premutational DNA lesion(s) remains to be identified. To investigate further the basic differences in UVA and UVB carcinogenesis, we compared in vivo cellular responses, viz. cell cycle progression and transient p53 expression in the epidermis, after UVA1 (340-400 nm) exposure with those after broadband UVB exposure of hairless mice. Using flow cytometry we found a temporary suppression of bromodeoxyuridine (BrdU) uptake in S-phase cells both after UVB and UVA1 irradiation, which only in the case of UVB is followed by an increase to well over control levels. With equally erythemogenic doses (1-2 MED), the modulation of BrdU uptake was more profound after UVB than after UVA1 irradiation. Also, a marked transient increase in the percentage of S-phase cells occurred both after UVB and after UVA1 irradiation, but this increase evolved more rapidly after UVA1 irradiation. Further, p53 expression increased both after UVB and UVA1 irradiations, with peak expression already occurring from 12 to 24 h after UVA1 exposure and around 24 h after UVB exposure. Overall, UVA1 radiation appears to have less of an impact on the cell cycle than UVB radiation, as measured by the magnitude and duration of changes in DNA synthesis and cells in S phase. These differences are likely to reflect basic differences between UVB and UVA1 in genotoxicity and carcinogenic action." @default.
• W2095349231 created "2016-06-24" @default.
• W2095349231 creator A5019483239 @default.
• W2095349231 creator A5040759016 @default.
• W2095349231 creator A5078613612 @default.
• W2095349231 date "1997-04-01" @default.
• W2095349231 modified "2023-09-27" @default.
• W2095349231 title "Cell Cycle Effects and Concomitant p53 Expression in Hairless Murine Skin after Longwave UVA (365 nm) Irradiation: A Comparison with UVB Irradiation" @default.
• W2095349231 cites W1509868163 @default.
• W2095349231 cites W1659382355 @default.
• W2095349231 cites W1963501271 @default.
• W2095349231 cites W1965213997 @default.
• W2095349231 cites W1972356947 @default.
• W2095349231 cites W1976127826 @default.
• W2095349231 cites W1976796682 @default.
• W2095349231 cites W1977934077 @default.
• W2095349231 cites W1993358791 @default.
• W2095349231 cites W1996040493 @default.
• W2095349231 cites W2012053348 @default.
• W2095349231 cites W2012732349 @default.
• W2095349231 cites W2016107093 @default.
• W2095349231 cites W2017045516 @default.
• W2095349231 cites W2023000504 @default.
• W2095349231 cites W2027838981 @default.
• W2095349231 cites W2032347639 @default.
• W2095349231 cites W2036009794 @default.
• W2095349231 cites W2037650684 @default.
• W2095349231 cites W2037670899 @default.
• W2095349231 cites W2074734750 @default.
• W2095349231 cites W2079542561 @default.
• W2095349231 cites W2108202116 @default.
• W2095349231 cites W2121883969 @default.
• W2095349231 cites W2147242002 @default.
• W2095349231 cites W2151160119 @default.
• W2095349231 cites W2153043020 @default.
• W2095349231 cites W2184000058 @default.
• W2095349231 cites W282058052 @default.
• W2095349231 doi "https://doi.org/10.1111/j.1751-1097.1997.tb01917.x" @default.
• W2095349231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9114751" @default.
• W2095349231 hasPublicationYear "1997" @default.
• W2095349231 type Work @default.
• W2095349231 sameAs 2095349231 @default.
• W2095349231 citedByCount "32" @default.
• W2095349231 countsByYear W20953492312012 @default.
• W2095349231 countsByYear W20953492312013 @default.
• W2095349231 countsByYear W20953492312014 @default.
• W2095349231 crossrefType "journal-article" @default.
• W2095349231 hasAuthorship W2095349231A5019483239 @default.
• W2095349231 hasAuthorship W2095349231A5040759016 @default.
• W2095349231 hasAuthorship W2095349231A5078613612 @default.
• W2095349231 hasConcept C104317684 @default.
• W2095349231 hasConcept C105702510 @default.
• W2095349231 hasConcept C111337013 @default.
• W2095349231 hasConcept C114246631 @default.
• W2095349231 hasConcept C121332964 @default.
• W2095349231 hasConcept C143425029 @default.
• W2095349231 hasConcept C1491633281 @default.
• W2095349231 hasConcept C150903083 @default.
• W2095349231 hasConcept C153911025 @default.
• W2095349231 hasConcept C185544564 @default.
• W2095349231 hasConcept C185592680 @default.
• W2095349231 hasConcept C207001950 @default.
• W2095349231 hasConcept C2776458125 @default.
• W2095349231 hasConcept C2779156968 @default.
• W2095349231 hasConcept C29537977 @default.
• W2095349231 hasConcept C552990157 @default.
• W2095349231 hasConcept C553184892 @default.
• W2095349231 hasConcept C55493867 @default.
• W2095349231 hasConcept C555283112 @default.
• W2095349231 hasConcept C86803240 @default.
• W2095349231 hasConceptScore W2095349231C104317684 @default.
• W2095349231 hasConceptScore W2095349231C105702510 @default.
• W2095349231 hasConceptScore W2095349231C111337013 @default.
• W2095349231 hasConceptScore W2095349231C114246631 @default.
• W2095349231 hasConceptScore W2095349231C121332964 @default.
• W2095349231 hasConceptScore W2095349231C143425029 @default.
• W2095349231 hasConceptScore W2095349231C1491633281 @default.
• W2095349231 hasConceptScore W2095349231C150903083 @default.
• W2095349231 hasConceptScore W2095349231C153911025 @default.
• W2095349231 hasConceptScore W2095349231C185544564 @default.
• W2095349231 hasConceptScore W2095349231C185592680 @default.
• W2095349231 hasConceptScore W2095349231C207001950 @default.
• W2095349231 hasConceptScore W2095349231C2776458125 @default.
• W2095349231 hasConceptScore W2095349231C2779156968 @default.
• W2095349231 hasConceptScore W2095349231C29537977 @default.
• W2095349231 hasConceptScore W2095349231C552990157 @default.
• W2095349231 hasConceptScore W2095349231C553184892 @default.
• W2095349231 hasConceptScore W2095349231C55493867 @default.
• W2095349231 hasConceptScore W2095349231C555283112 @default.
• W2095349231 hasConceptScore W2095349231C86803240 @default.
• W2095349231 hasIssue "4" @default.
• W2095349231 hasLocation W20953492311 @default.
• W2095349231 hasLocation W20953492312 @default.
• W2095349231 hasOpenAccess W2095349231 @default.
• W2095349231 hasPrimaryLocation W20953492311 @default.
• W2095349231 hasRelatedWork W1531082209 @default.
• W2095349231 hasRelatedWork W1546448538 @default.
• W2095349231 hasRelatedWork W1990818827 @default.

• next