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- W2095360868 abstract "The emphasis in aminoglycoside therapy should be obtaining an adequate peak and avoiding any measurable through concentration. This can best be done by dosing these agents every 12 hours or even once per day. There may be occasions when more frequent dosing is needed such as in burn patients or cystic fibrosis patients. The aminoglycoside should be infused over a 30 minute period to avoid neuromuscular toxicity. Neutropenic patients should have an appropriate β-lactam agent added to their aminoglycoside. This approach is currently being used. Even with a single, large daily dose, aminoglycosides are effective with minimal toxic effects." @default.
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- W2095360868 date "1990-02-01" @default.
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- W2095360868 title "Comments on the optimal use of aminoglycosides" @default.
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- W2095360868 doi "https://doi.org/10.1016/0278-2316(90)90011-4" @default.
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