Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095372202> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2095372202 abstract "2-Ethyl-1-hexanol (2-EH) was nominated for carcinogenicity testing by the National Toxicology Program because it is a high-volume chemical and a major metabolite of di(2-ethylhexyl)phthalate, a known hepatocarcinogen and a known contaminant in blood storage bags. In addition to uses as an intermediate in the manufacture of plasticizers. 2-EH is also used as a solvent, a lubricant and as a finishing compound for paper and textiles. The preferred route of administration for the carcinogenicity studies was oral via the diet. However, feed blends containing neat 2-EH were not sufficiently stable for feed studies. Dosed feed blends prepared with neat 2-EH retained only 86% of the theoretical concentration after blending, and 46% of theoretical after storage for 2 days in a rat cage environment. Feed blends containing microencapsulated 2-EH were sufficiently stable for toxicity studies: no losses of 2-EH were observed after blending, feed blends stored for 7 days in a rat cage retained 99% of the theoretical concentration and blends stored in sealed containers at room temperature for 21 days retained 97% of the theoretical concentration. These studies demonstrate the potential for microencapsulation technology to eliminate dose formulation problems associated with volatile chemicals." @default.
- W2095372202 created "2016-06-24" @default.
- W2095372202 creator A5045785458 @default.
- W2095372202 creator A5065397816 @default.
- W2095372202 creator A5070183920 @default.
- W2095372202 date "1995-01-01" @default.
- W2095372202 modified "2023-10-16" @default.
- W2095372202 title "Analysis of feed blends containing microencapsulated 2-ethyl-1-hexanol: Verification of homogeneity and stability" @default.
- W2095372202 cites W1503187067 @default.
- W2095372202 cites W2014016832 @default.
- W2095372202 cites W2016213348 @default.
- W2095372202 cites W2062718001 @default.
- W2095372202 cites W2092122739 @default.
- W2095372202 doi "https://doi.org/10.1002/jat.2550150103" @default.
- W2095372202 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7745219" @default.
- W2095372202 hasPublicationYear "1995" @default.
- W2095372202 type Work @default.
- W2095372202 sameAs 2095372202 @default.
- W2095372202 citedByCount "4" @default.
- W2095372202 crossrefType "journal-article" @default.
- W2095372202 hasAuthorship W2095372202A5045785458 @default.
- W2095372202 hasAuthorship W2095372202A5065397816 @default.
- W2095372202 hasAuthorship W2095372202A5070183920 @default.
- W2095372202 hasConcept C178790620 @default.
- W2095372202 hasConcept C185592680 @default.
- W2095372202 hasConcept C2780471494 @default.
- W2095372202 hasConcept C2780874159 @default.
- W2095372202 hasConcept C2781005124 @default.
- W2095372202 hasConcept C31903555 @default.
- W2095372202 hasConcept C43617362 @default.
- W2095372202 hasConcept C58968531 @default.
- W2095372202 hasConceptScore W2095372202C178790620 @default.
- W2095372202 hasConceptScore W2095372202C185592680 @default.
- W2095372202 hasConceptScore W2095372202C2780471494 @default.
- W2095372202 hasConceptScore W2095372202C2780874159 @default.
- W2095372202 hasConceptScore W2095372202C2781005124 @default.
- W2095372202 hasConceptScore W2095372202C31903555 @default.
- W2095372202 hasConceptScore W2095372202C43617362 @default.
- W2095372202 hasConceptScore W2095372202C58968531 @default.
- W2095372202 hasLocation W20953722021 @default.
- W2095372202 hasLocation W20953722022 @default.
- W2095372202 hasOpenAccess W2095372202 @default.
- W2095372202 hasPrimaryLocation W20953722021 @default.
- W2095372202 hasRelatedWork W1968511602 @default.
- W2095372202 hasRelatedWork W1994156947 @default.
- W2095372202 hasRelatedWork W2011763773 @default.
- W2095372202 hasRelatedWork W2022236476 @default.
- W2095372202 hasRelatedWork W2037592612 @default.
- W2095372202 hasRelatedWork W2054003038 @default.
- W2095372202 hasRelatedWork W2102160299 @default.
- W2095372202 hasRelatedWork W2386203691 @default.
- W2095372202 hasRelatedWork W2396464215 @default.
- W2095372202 hasRelatedWork W4224259833 @default.
- W2095372202 isParatext "false" @default.
- W2095372202 isRetracted "false" @default.
- W2095372202 magId "2095372202" @default.
- W2095372202 workType "article" @default.