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- W2095381171 abstract "T wo paradigms—breast cancer initially as a local and regional disease or breast cancer initially as a systemic disease—have affected the approach to detection and treatment of breast cancer throughout history. If breast cancer is a local/regional disease process, then there is a role for the surgeon in its cure. If breast cancer is a systemic disease, then surgery alone cannot cure it, and any cure must come from systemic treatments. If over time breast cancer progresses from a local disease to a systemic disease, then there may be a role for earlier detection of breast cancer. The history of thinking about breast cancer as I narrate it will be highly colored by my own experience. I make no apologies for that. Every historian brings his own experiences and biases to the retelling of the past. My interest in the breast cancer problem goes back more than 40 years. I have been involved in research studies related to the treatment of breast cancer with surgery, with radiotherapy, with endocrine therapy, and with chemotherapy. I have also been involved in studies evaluating the role of earlier detection. My review will also allow me to reflect upon my own career and to acknowledge some of the mentors on whose shoulders I have stood." @default.
- W2095381171 created "2016-06-24" @default.
- W2095381171 creator A5060619351 @default.
- W2095381171 date "2003-04-01" @default.
- W2095381171 modified "2023-09-27" @default.
- W2095381171 title "Breast Cancer Detection and Treatment" @default.
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- W2095381171 doi "https://doi.org/10.1001/archsurg.138.4.397" @default.
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