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- W2095383453 abstract "Abstract Treatment of day 8 pregnant rats for 3 days with 30 mg aminoglutethimide, an inhibitor of steroid biosynthesis, did not affect gestation but when administered with as little as 0.1 μg of estradiol-17β, abortion occurred in 50% of the animals. At 0.5 μg or higher doses of estradiol-17β and the same dose of aminoglutethimide, abortion occurred in all animals. This effect was reversed by simultaneous treatment with progesterone. AGP (30 mg) reduced progesterone, 20α-dihydroprogesterone and estrogen concentration in peripheral plasma by 30, 50 and 50%, 6 hours after a single injection." @default.
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- W2095383453 date "1971-10-01" @default.
- W2095383453 modified "2023-09-25" @default.
- W2095383453 title "Aminoglutethimide potentiation of estrogen-induced abortion" @default.
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- W2095383453 doi "https://doi.org/10.1016/0010-7824(71)90078-3" @default.
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