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- W2095407871 abstract "Cerebral vascular endothelial cells (EC) isolated from human brain do not constitutively express class II MHC antigens. However, incubation in the presence of human interferon-gamma (IFNγ) resulted in the expression of both HLA-DR and -DP antigens. FACS analysis revealed that approximately 40% of the EC population expressed HLA-DR antigen. Quantitation by ELISA demonstrated that maximum expression was observed with 100 U/ml IFNγ for 4 days. Treatment with IFNγ also increased class II mRNA levels in all EC cultures tested." @default.
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- W2095407871 date "1991-12-01" @default.
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- W2095407871 title "Class II MHC antigen expression by cultured human cerebral vascular endothelial cells" @default.
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- W2095407871 doi "https://doi.org/10.1016/0006-8993(91)91718-g" @default.
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