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• W2095422075 endingPage "2083" @default.
• W2095422075 startingPage "2073" @default.
• W2095422075 abstract "Six subjects underwent PET scans while they performed three versions of a recognition memory test for words and three versions of a control task. In each memory condition, the subjects discriminated between words presented in a prescan study list and words new to the experiment. During the 30 s scanning interval, the ratio of old and new words was 0: 20, 4: 16 or 16: 4, depending on the experimental condition. Outside this interval, the ratio was 50: 50 in all three conditions. The requirement in the control task was to discriminate between two character strings, the ratios of which were also manipulated during the 30 s scanning interval. Employing the control task as a covariate, analysis with statistical parametric mapping revealed that regional cerebral blood flow (rCBF) covaried with increasing density of old items in three regions of prefrontal cortex: right dorsolateral [Brodmann area (BA) 9/46], right medial (BA 32/8) and bilateral frontopolar cortex (BA 10). It is concluded that the prefrontal cortex, especially in the right hemisphere, is more active when a retrieval attempt succeeds than when it fails. This finding is consistent with the idea that the prefrontal cortex supports processes that operate selectively on the products of memory retrieval." @default.
• W2095422075 created "2016-06-24" @default.
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• W2095422075 date "1996-01-01" @default.
• W2095422075 modified "2023-10-14" @default.
• W2095422075 title "Differential activation of the prefrontal cortex in successful and unsuccessful memory retrieval" @default.
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• W2095422075 doi "https://doi.org/10.1093/brain/119.6.2073" @default.
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