FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095426017> ?p ?o ?g. }

• W2095426017 endingPage "799" @default.
• W2095426017 startingPage "790" @default.
• W2095426017 abstract "To determine whether testosterone depletion in males before trauma-hemorrhage has any salutary effects on cardiac performance after hemorrhage and resuscitation.Studies indicate that castration of male mice before trauma-hemorrhage prevents the immunodepression seen after hemorrhage and resuscitation. However, the effect of precastration on cardiac performance under such conditions remains unknown.Male rats were castrated or sham-castrated 14 days before the experiment. After laparotomy (i.e., induction of trauma), the rats were bled to and maintained at a mean arterial pressure of 40 mm Hg until 40% of the maximal shed volume was returned in the form of Ringer's lactate solution. The animals were then resuscitated with four times the shed blood volume with Ringer's lactate solution over 60 minutes. Heart performance was measured using a left ventricular catheter connected to an in vivo heart performance analyzer. Indices of left ventricular performance (i.e., maximal rate of the pressure increase [+dP/dt(max)] and decrease [-dP/dt(max)) were measured up to 4 hours after trauma, hemorrhagic shock, and resuscitation.In sham-castrated animals, trauma-hemorrhage and resuscitation decreased the in vivo heart performance as evidenced by the reduced values of +dP/dt(max) and -dP/dt(max). Precastrated animals, however, showed significantly higher values of +dP/dt(max) and -dP/dt(max) than sham-castrated animals after trauma-hemorrhage and resuscitation.Testosterone antagonism in males might be an effective approach for maintaining myocardial function after adverse circulatory conditions. Although testosterone depletion in male trauma victims is neither practical nor advocated, testosterone receptor blockade after trauma may represent a novel and useful adjunct for maintaining normal myocardial performance under those conditions." @default.
• W2095426017 created "2016-06-24" @default.
• W2095426017 creator A5022512059 @default.
• W2095426017 creator A5052126305 @default.
• W2095426017 creator A5066761803 @default.
• W2095426017 creator A5084834018 @default.
• W2095426017 creator A5084966628 @default.
• W2095426017 creator A5085171919 @default.
• W2095426017 date "1998-06-01" @default.
• W2095426017 modified "2023-09-23" @default.
• W2095426017 title "Testosterone: The Crucial Hormone Responsible for Depressing Myocardial Function in Males After Trauma-Hemorrhage" @default.
• W2095426017 cites W149936582 @default.
• W2095426017 cites W1831835471 @default.
• W2095426017 cites W1910433138 @default.
• W2095426017 cites W1964007673 @default.
• W2095426017 cites W1974604171 @default.
• W2095426017 cites W1979109569 @default.
• W2095426017 cites W1984631757 @default.
• W2095426017 cites W1996769397 @default.
• W2095426017 cites W2002819680 @default.
• W2095426017 cites W2003656057 @default.
• W2095426017 cites W2008499543 @default.
• W2095426017 cites W2015225665 @default.
• W2095426017 cites W2024860217 @default.
• W2095426017 cites W2034291878 @default.
• W2095426017 cites W2041194473 @default.
• W2095426017 cites W2046881607 @default.
• W2095426017 cites W2061106208 @default.
• W2095426017 cites W2062734471 @default.
• W2095426017 cites W2074962294 @default.
• W2095426017 cites W2080363833 @default.
• W2095426017 cites W2087695885 @default.
• W2095426017 cites W2124171275 @default.
• W2095426017 cites W2136300977 @default.
• W2095426017 cites W2163412727 @default.
• W2095426017 cites W2208681899 @default.
• W2095426017 cites W2215796820 @default.
• W2095426017 cites W2243947562 @default.
• W2095426017 cites W2253750847 @default.
• W2095426017 cites W2263205512 @default.
• W2095426017 cites W2313499625 @default.
• W2095426017 cites W2314052331 @default.
• W2095426017 cites W2317657138 @default.
• W2095426017 cites W2411780263 @default.
• W2095426017 cites W4236624503 @default.
• W2095426017 cites W4243939267 @default.
• W2095426017 cites W4294553892 @default.
• W2095426017 doi "https://doi.org/10.1097/00000658-199806000-00002" @default.
• W2095426017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1191378" @default.
• W2095426017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9637542" @default.
• W2095426017 hasPublicationYear "1998" @default.
• W2095426017 type Work @default.
• W2095426017 sameAs 2095426017 @default.
• W2095426017 citedByCount "88" @default.
• W2095426017 countsByYear W20954260172012 @default.
• W2095426017 countsByYear W20954260172013 @default.
• W2095426017 countsByYear W20954260172014 @default.
• W2095426017 countsByYear W20954260172015 @default.
• W2095426017 countsByYear W20954260172016 @default.
• W2095426017 countsByYear W20954260172017 @default.
• W2095426017 countsByYear W20954260172019 @default.
• W2095426017 countsByYear W20954260172020 @default.
• W2095426017 countsByYear W20954260172021 @default.
• W2095426017 countsByYear W20954260172022 @default.
• W2095426017 crossrefType "journal-article" @default.
• W2095426017 hasAuthorship W2095426017A5022512059 @default.
• W2095426017 hasAuthorship W2095426017A5052126305 @default.
• W2095426017 hasAuthorship W2095426017A5066761803 @default.
• W2095426017 hasAuthorship W2095426017A5084834018 @default.
• W2095426017 hasAuthorship W2095426017A5084966628 @default.
• W2095426017 hasAuthorship W2095426017A5085171919 @default.
• W2095426017 hasBestOaLocation W20954260172 @default.
• W2095426017 hasConcept C111566952 @default.
• W2095426017 hasConcept C126322002 @default.
• W2095426017 hasConcept C139940330 @default.
• W2095426017 hasConcept C164705383 @default.
• W2095426017 hasConcept C2777953023 @default.
• W2095426017 hasConcept C2778165595 @default.
• W2095426017 hasConcept C2778198053 @default.
• W2095426017 hasConcept C2779256933 @default.
• W2095426017 hasConcept C2779279991 @default.
• W2095426017 hasConcept C2781300812 @default.
• W2095426017 hasConcept C42219234 @default.
• W2095426017 hasConcept C71315377 @default.
• W2095426017 hasConcept C71924100 @default.
• W2095426017 hasConcept C84393581 @default.
• W2095426017 hasConceptScore W2095426017C111566952 @default.
• W2095426017 hasConceptScore W2095426017C126322002 @default.
• W2095426017 hasConceptScore W2095426017C139940330 @default.
• W2095426017 hasConceptScore W2095426017C164705383 @default.
• W2095426017 hasConceptScore W2095426017C2777953023 @default.
• W2095426017 hasConceptScore W2095426017C2778165595 @default.
• W2095426017 hasConceptScore W2095426017C2778198053 @default.
• W2095426017 hasConceptScore W2095426017C2779256933 @default.
• W2095426017 hasConceptScore W2095426017C2779279991 @default.
• W2095426017 hasConceptScore W2095426017C2781300812 @default.
• W2095426017 hasConceptScore W2095426017C42219234 @default.
• W2095426017 hasConceptScore W2095426017C71315377 @default.

• next