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- W2095432838 abstract "Introduction: CXCR4 is a G-protein coupled receptor that has been linked with metastasis in several cancers, including breast cancer. We recently demonstrated that high CXCR4 level in primary tumors of patients with breast cancer had a prognostic significance. What is not known, however, is whether CXCR4 can predict response to chemotherapy. We hypothesize that patients whose tumors had a low CXCR4 overexpression level following neoadjuvant chemotherapy will have a lower recurrence rate than those whose tumors had persistently high CXCR4 levels." @default.
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- W2095432838 date "2010-02-01" @default.
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- W2095432838 title "Persistently Elevated Chemokine Receptor CXCR4 in Primary Tumors Following Neoadjuvant Chemotherapy Is a Novel Predictive Molecular Marker for Patients with Locally Advanced Breast Cancer" @default.
- W2095432838 doi "https://doi.org/10.1016/j.jss.2009.11.065" @default.
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