FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095435404> ?p ?o ?g. }

• W2095435404 endingPage "675" @default.
• W2095435404 startingPage "668" @default.
• W2095435404 abstract "Aims In this randomized, double-blind clinical study, we investigated the relationship between autoantibodies against cardiac troponin I (cTnI) and disease severity in elderly congestive heart failure (CHF) patients before and after titration of beta-blocker therapy. Methods and results Anti-cTnI, cTnI, and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in blood from 138 patients (73 ± 5.6 years, 48% male) with CHF in American Heart Association stages A–C were measured at baseline and after titration of beta-blockers to maximal tolerated dose. Median follow-up period was 85 days. Anti-cTnI was measured using an experimental assay (Abbott Diagnostics) and is expressed as a relative value unit (RVU) in relation to the mean value of a low-level control sample. Anti-cTnI values in CHF patients were also compared with measurements taken in a normal reference population of 300 healthy individuals (50% male). Cardiac troponin I and NT-proBNP levels were measured using routine assays (Architect® Abbott Diagnostics and Roche Diagnostics®). Median anti-cTnI was 0.53 and 0.56 RVU in healthy and CHF subjects, respectively (P = n.s.), and increased significantly to 0.67 RVU (P < 0.001) after beta-blocker titration. Mean cTnI values were 0.021 µg/L at baseline and fell significantly to 0.0046 µg/L at follow-up (P < 0.001). Median NT-proBNP values were 352 ng/L at baseline and 414 ng/L after titration (P = n.s.). In contrast to NT-proBNP and cTnI, anti-cTnI was not associated with the severity of CHF at baseline or follow-up. Conclusion Levels of anti-cTnI tend to increase in elderly patients with CHF following titration of beta-blocker therapy but do not correlate with disease severity. Anti-cTnI is not a useful biomarker for heart failure diagnosis, prognosis, or monitoring. In contrast, levels of cTnI decreased following therapy and did correlate with disease severity." @default.
• W2095435404 created "2016-06-24" @default.
• W2095435404 creator A5001199933 @default.
• W2095435404 creator A5007334158 @default.
• W2095435404 creator A5012414631 @default.
• W2095435404 creator A5018328821 @default.
• W2095435404 creator A5018563051 @default.
• W2095435404 creator A5036289535 @default.
• W2095435404 creator A5036856555 @default.
• W2095435404 creator A5037097997 @default.
• W2095435404 creator A5066482754 @default.
• W2095435404 date "2010-07-01" @default.
• W2095435404 modified "2023-10-02" @default.
• W2095435404 title "Autoantibodies against cardiac troponin I in patients with congestive heart failure" @default.
• W2095435404 cites W1967595093 @default.
• W2095435404 cites W1969337909 @default.
• W2095435404 cites W1972076391 @default.
• W2095435404 cites W1979717207 @default.
• W2095435404 cites W1988816170 @default.
• W2095435404 cites W1993630991 @default.
• W2095435404 cites W2026515462 @default.
• W2095435404 cites W2039229911 @default.
• W2095435404 cites W2046928483 @default.
• W2095435404 cites W2052826219 @default.
• W2095435404 cites W2059285802 @default.
• W2095435404 cites W2077067449 @default.
• W2095435404 cites W2081653888 @default.
• W2095435404 cites W2087666753 @default.
• W2095435404 cites W2090544953 @default.
• W2095435404 cites W2094650584 @default.
• W2095435404 cites W2098853737 @default.
• W2095435404 cites W2100812517 @default.
• W2095435404 cites W2109643322 @default.
• W2095435404 cites W2111936495 @default.
• W2095435404 cites W2118057012 @default.
• W2095435404 cites W2132182315 @default.
• W2095435404 cites W2140419562 @default.
• W2095435404 cites W2152776328 @default.
• W2095435404 cites W2163052819 @default.
• W2095435404 cites W2164285209 @default.
• W2095435404 cites W2167666858 @default.
• W2095435404 cites W2336198476 @default.
• W2095435404 cites W4255009698 @default.
• W2095435404 doi "https://doi.org/10.1093/eurjhf/hfq088" @default.
• W2095435404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20513750" @default.
• W2095435404 hasPublicationYear "2010" @default.
• W2095435404 type Work @default.
• W2095435404 sameAs 2095435404 @default.
• W2095435404 citedByCount "17" @default.
• W2095435404 countsByYear W20954354042012 @default.
• W2095435404 countsByYear W20954354042013 @default.
• W2095435404 countsByYear W20954354042014 @default.
• W2095435404 countsByYear W20954354042016 @default.
• W2095435404 countsByYear W20954354042017 @default.
• W2095435404 countsByYear W20954354042018 @default.
• W2095435404 crossrefType "journal-article" @default.
• W2095435404 hasAuthorship W2095435404A5001199933 @default.
• W2095435404 hasAuthorship W2095435404A5007334158 @default.
• W2095435404 hasAuthorship W2095435404A5012414631 @default.
• W2095435404 hasAuthorship W2095435404A5018328821 @default.
• W2095435404 hasAuthorship W2095435404A5018563051 @default.
• W2095435404 hasAuthorship W2095435404A5036289535 @default.
• W2095435404 hasAuthorship W2095435404A5036856555 @default.
• W2095435404 hasAuthorship W2095435404A5037097997 @default.
• W2095435404 hasAuthorship W2095435404A5066482754 @default.
• W2095435404 hasConcept C115725540 @default.
• W2095435404 hasConcept C126322002 @default.
• W2095435404 hasConcept C164705383 @default.
• W2095435404 hasConcept C2775915353 @default.
• W2095435404 hasConcept C2778198053 @default.
• W2095435404 hasConcept C2908647359 @default.
• W2095435404 hasConcept C36036425 @default.
• W2095435404 hasConcept C500558357 @default.
• W2095435404 hasConcept C71924100 @default.
• W2095435404 hasConcept C99454951 @default.
• W2095435404 hasConceptScore W2095435404C115725540 @default.
• W2095435404 hasConceptScore W2095435404C126322002 @default.
• W2095435404 hasConceptScore W2095435404C164705383 @default.
• W2095435404 hasConceptScore W2095435404C2775915353 @default.
• W2095435404 hasConceptScore W2095435404C2778198053 @default.
• W2095435404 hasConceptScore W2095435404C2908647359 @default.
• W2095435404 hasConceptScore W2095435404C36036425 @default.
• W2095435404 hasConceptScore W2095435404C500558357 @default.
• W2095435404 hasConceptScore W2095435404C71924100 @default.
• W2095435404 hasConceptScore W2095435404C99454951 @default.
• W2095435404 hasIssue "7" @default.
• W2095435404 hasLocation W20954354041 @default.
• W2095435404 hasLocation W20954354042 @default.
• W2095435404 hasOpenAccess W2095435404 @default.
• W2095435404 hasPrimaryLocation W20954354041 @default.
• W2095435404 hasRelatedWork W2067492678 @default.
• W2095435404 hasRelatedWork W2125804349 @default.
• W2095435404 hasRelatedWork W2170496161 @default.
• W2095435404 hasRelatedWork W2184963913 @default.
• W2095435404 hasRelatedWork W2357615119 @default.
• W2095435404 hasRelatedWork W2382347200 @default.
• W2095435404 hasRelatedWork W2383511568 @default.
• W2095435404 hasRelatedWork W2392149260 @default.

• next