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- W2095524792 abstract "The binding affinities of a series of D-galactose-terminated glycerol glycosides and oligosaccharides for the asialoglycoprotein receptor isolated from rabbit liver were determined in vitro using a radioreceptor-inhibition assay with 125I-asialoorosomucoid. The relative affinities of the synthetic ligands increased with the number of exposed D-galactose termini. Of the compounds examined, 1,2,3-tri-O-beta-lactosylglycerol associated with the greatest affinity (estimated Kd = 7.97 x 10(-5) M). Examination of the affinities of the synthetic series indicated that both the number and propinquity of the D-galactose termini influenced the strength of the binding interactions." @default.
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- W2095524792 date "1994-02-01" @default.
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- W2095524792 title "Binding of d-galactose-terminated ligands to rabbit asialoglycoprotein receptor" @default.
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- W2095524792 doi "https://doi.org/10.1016/0008-6215(94)84258-2" @default.
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