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• W2095550689 abstract "Although cervical carcinoma is among the most frequently encountered malignancies during pregnancy only a small number of cases during pregnancy have been reported. Usually, the patients have been treated by radical trachelectomy with or without chemotherapy during the pregnancy. Laparoscopic pelvic lymph node dissection with frozen section, simple trachelectomy and cerclage were performed in the 22(nd) week of pregnancy. The histologic examination confirmed a squamous cell carcinoma of the cervix of 35mm diameter, lymphangioinvasion (L1), low grade, clear surgical margin, negative pelvic lymph nodes according to stage Figo IB. Adjuvant chemotherapy with three cycles of cisplatin was performed after surgery. Delivery was performed by cesarean section followed by radical hysterectomy in the the 32(nd) week of pregnancy. Recurrent adjuvant chemotherapy with three cycles of cisplatin and local vaginal iridium radiation were performed after surgery. Patient had no surgery related complications. No relapse of cancer has been diagnosed during the following 16 months. Simple trachelectomy may be alternative treatment option to radical trachelectomy for pregnant women with early stage cervical cancer without lymph node metastasis. Servikal karsinoma gebelik süresince en sık karşılaşılan maligniteler arasında olmasına rağmen gebelik süresince olguların sadece küçük bir kısmı rapor edilmektedir. Genellikle, hastalar gebelik sırasında kemoterapi ile birlikte ya da kemoterapi olmaksızın radikal trakelektomi ile tedavi edilmektedir.Donmuş kesit (frozen section) ile laparoskopik pelvik lenf nodu diseksiyonu, basit trakelektomi ve serklaj gebeliğin 22. haftasında gerçekleştirildi. Histolojik inceleme; lenfanjiyoinvazyon (L1), düşük derece, temiz cerrahi sınır, negatif pelvik lenf nodları ile FİGO IB evresine uyan, 35 mm çapında serviksin yassı hücreli karsinomunu doğruladı. Cerrahiden sonra üç döngü sisplatin ile adjuvan kemoterapi uygulandı. Doğum gebeliğin 32. haftasında sezaryen ile ve takibinde radikal histerektomi ile gerçekleştirildi. Cerrahiden sonra üç döngü sisplatin ile yinelenen adjuvan kemoterapi ve lokal vajinal iridyum ışınlaması yapıldı. Hastada cerrahi ile ilişkili komplikasyonlar olmadı. İzleyen 16 ay süresince kanser tekrarı tanısı konmadı.Basit trakelektomi lenf nodu metastazı olmayan erken evre serviks kanserli gebe kadınlar için radikal trakelektomiye alternatif tedavi seçeneği olabilir." @default.
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• W2095550689 date "2011-06-01" @default.
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• W2095550689 title "Simple trachelectomy of early invasive cervix carcinoma in the second trimester" @default.
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• W2095550689 doi "https://doi.org/10.5152/jtgga.2011.27" @default.
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