Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095577184> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2095577184 endingPage "308" @default.
- W2095577184 startingPage "304" @default.
- W2095577184 abstract "Abstract Phagocytosis is a central event in the innate immune responses that are triggered by the association between ligands on the surface of pathogens and receptors on the membrane of phagocytes. Particularly, complement‐mediated phagocytosis is accomplished by specific recognition of bound complement components by the corresponding complement receptors on the phagocytes. The protein‐tyrosine kinase, Syk, plays a central role in Fcγ receptor‐mediated phagocytosis in the adaptive immune system. From recent studies using a macrophage‐like differentiated cell line and serum‐treated zymosan, it was found that Syk also plays an essential role in complement‐mediated phagocytosis in innate immunity. Serum‐treated zymosan particles promptly attached to the cells and were subsequently engulfed via complement receptor3. During this process, Syk became tyrosine‐phosphorylated and accumulated around the nascent phagosomes. The transfer of Syk‐siRNA or dominant‐negative Syk (DN‐Syk) into macrophages resulted in impaired engulfment of pathogen. Collectively, Syk is required for the engulfment of pathogen in complement‐mediated phagocytosis. iubmb Life, 58: 304‐308, 2006" @default.
- W2095577184 created "2016-06-24" @default.
- W2095577184 creator A5017442070 @default.
- W2095577184 creator A5063421059 @default.
- W2095577184 date "2006-05-01" @default.
- W2095577184 modified "2023-10-17" @default.
- W2095577184 title "Complement‐mediated phagocytosis ‐ the role of Syk" @default.
- W2095577184 cites W1481629090 @default.
- W2095577184 cites W1955568895 @default.
- W2095577184 cites W1995900983 @default.
- W2095577184 cites W2067235043 @default.
- W2095577184 cites W2078991312 @default.
- W2095577184 cites W2157943033 @default.
- W2095577184 doi "https://doi.org/10.1080/15216540600746377" @default.
- W2095577184 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16754322" @default.
- W2095577184 hasPublicationYear "2006" @default.
- W2095577184 type Work @default.
- W2095577184 sameAs 2095577184 @default.
- W2095577184 citedByCount "45" @default.
- W2095577184 countsByYear W20955771842012 @default.
- W2095577184 countsByYear W20955771842013 @default.
- W2095577184 countsByYear W20955771842014 @default.
- W2095577184 countsByYear W20955771842015 @default.
- W2095577184 countsByYear W20955771842016 @default.
- W2095577184 countsByYear W20955771842017 @default.
- W2095577184 countsByYear W20955771842018 @default.
- W2095577184 countsByYear W20955771842019 @default.
- W2095577184 countsByYear W20955771842020 @default.
- W2095577184 countsByYear W20955771842021 @default.
- W2095577184 countsByYear W20955771842022 @default.
- W2095577184 countsByYear W20955771842023 @default.
- W2095577184 crossrefType "journal-article" @default.
- W2095577184 hasAuthorship W2095577184A5017442070 @default.
- W2095577184 hasAuthorship W2095577184A5063421059 @default.
- W2095577184 hasConcept C111684460 @default.
- W2095577184 hasConcept C136449434 @default.
- W2095577184 hasConcept C160448771 @default.
- W2095577184 hasConcept C161478664 @default.
- W2095577184 hasConcept C175773311 @default.
- W2095577184 hasConcept C202751555 @default.
- W2095577184 hasConcept C203014093 @default.
- W2095577184 hasConcept C2778870864 @default.
- W2095577184 hasConcept C2779244956 @default.
- W2095577184 hasConcept C2779931124 @default.
- W2095577184 hasConcept C35174551 @default.
- W2095577184 hasConcept C42362537 @default.
- W2095577184 hasConcept C55493867 @default.
- W2095577184 hasConcept C62478195 @default.
- W2095577184 hasConcept C86803240 @default.
- W2095577184 hasConcept C8891405 @default.
- W2095577184 hasConcept C89372155 @default.
- W2095577184 hasConcept C95444343 @default.
- W2095577184 hasConceptScore W2095577184C111684460 @default.
- W2095577184 hasConceptScore W2095577184C136449434 @default.
- W2095577184 hasConceptScore W2095577184C160448771 @default.
- W2095577184 hasConceptScore W2095577184C161478664 @default.
- W2095577184 hasConceptScore W2095577184C175773311 @default.
- W2095577184 hasConceptScore W2095577184C202751555 @default.
- W2095577184 hasConceptScore W2095577184C203014093 @default.
- W2095577184 hasConceptScore W2095577184C2778870864 @default.
- W2095577184 hasConceptScore W2095577184C2779244956 @default.
- W2095577184 hasConceptScore W2095577184C2779931124 @default.
- W2095577184 hasConceptScore W2095577184C35174551 @default.
- W2095577184 hasConceptScore W2095577184C42362537 @default.
- W2095577184 hasConceptScore W2095577184C55493867 @default.
- W2095577184 hasConceptScore W2095577184C62478195 @default.
- W2095577184 hasConceptScore W2095577184C86803240 @default.
- W2095577184 hasConceptScore W2095577184C8891405 @default.
- W2095577184 hasConceptScore W2095577184C89372155 @default.
- W2095577184 hasConceptScore W2095577184C95444343 @default.
- W2095577184 hasIssue "5-6" @default.
- W2095577184 hasLocation W20955771841 @default.
- W2095577184 hasLocation W20955771842 @default.
- W2095577184 hasOpenAccess W2095577184 @default.
- W2095577184 hasPrimaryLocation W20955771841 @default.
- W2095577184 hasRelatedWork W1954296697 @default.
- W2095577184 hasRelatedWork W2070650369 @default.
- W2095577184 hasRelatedWork W2095577184 @default.
- W2095577184 hasRelatedWork W2096689375 @default.
- W2095577184 hasRelatedWork W2149706167 @default.
- W2095577184 hasRelatedWork W2155185836 @default.
- W2095577184 hasRelatedWork W2167718800 @default.
- W2095577184 hasRelatedWork W2474315339 @default.
- W2095577184 hasRelatedWork W3016691675 @default.
- W2095577184 hasRelatedWork W323482686 @default.
- W2095577184 hasVolume "58" @default.
- W2095577184 isParatext "false" @default.
- W2095577184 isRetracted "false" @default.
- W2095577184 magId "2095577184" @default.
- W2095577184 workType "article" @default.