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- W2095590660 abstract "To determine the effect of certain compounds associated with bacterial overgrowth on jejunal mucosa, we studied the changes in morphology, protein synthesis, amino acid transport, and brush border enzyme levels produced by deoxycholate, bacterial endotoxin, and indole in an organ culture system. Rabbit jejunal biopsies incubated for 24 hr in medium containing 1 mm deoxycholate showed complete loss of villous architecture, dissolution of cell structure, and marked impairment of protein synthesis and amino acid transport, without significant change in brush border enzyme activity. Incubation of jejunal cultures in lower concentrations of deoxycholate, indole, or bacterial endotoxin resulted in minor morphological alterations, but in no functional differences compared with controls." @default.
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- W2095590660 title "Effect of Deoxycholate, Indole, and Endotoxin on Organ Cultures of Rabbit Jejunum" @default.
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- W2095590660 doi "https://doi.org/10.1016/s0016-5085(74)80176-9" @default.
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