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• W2095593366 abstract "We report on a woman with an Lp(a) lipoprotein level above the 99th centile of the population distribution of concentrations, who at the age of 43 had had deep vein thrombosis causing a pulmonary embolus and whose brother, who also had a very high level, had suffered a cerebral infarction at the age of 43. She had given birth to three children, all with very low birth weight, one of whom died when 3 months old. The placentas had been small and ischemic. The concurrence of a very high Lp(a) lipoprotein level, familial thromboembolic disease and recurrent placental ischemia with delivery of children with low birth weight suggests the possibility that a very high Lp(a) lipoprotein concentration may predispose to placental insufficiency, presumably arising from pathological changes in maternal uterine vessels in the placental bed. If confirmed, a very high Lp(a) lipoprotein level may be a factor to consider in women who have repeated pregnancies with placental insufficiency and who give birth to children with low birth weight." @default.
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• W2095593366 date "2008-06-28" @default.
• W2095593366 modified "2023-10-16" @default.
• W2095593366 title "High Lp(a) lipoprotein level in maternal serum may interfere with placental circulation and cause fetal growth retardation" @default.
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• W2095593366 doi "https://doi.org/10.1111/j.1399-0004.1994.tb04202.x" @default.
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