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- W2095621184 abstract "A sensitive and selective method has been developed for the determination of ritodrine diastereomers in human serum using high-performance liquid chromatography with a chiral stationary phase column and a fluorescence detector. No interfering peaks from endogenous substances were observed. The method showed good reproducibility and accuracy, and the standard curve was linear up to 100 ng/mL with a correlation coefficient of 0.999. Limit of detection (signal-to-noise = 3) and quantitation (signal-to-noise = 10) were found to be 2 and 5 ng/mL, respectively. This method is suitable for chiral pharmacological and pharmacokinetic studies as well as the therapeutic drug monitoring of ritodrine diastereomers for which no information currently exists." @default.
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- W2095621184 date "2010-07-01" @default.
- W2095621184 modified "2023-10-18" @default.
- W2095621184 title "Stereoselective Analysis of Ritodrine Diastereomers in Human Serum Using HPLC" @default.
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- W2095621184 doi "https://doi.org/10.1093/chromsci/48.6.503" @default.
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