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- W2095632337 abstract "Summary We report on a case of ectopic Cushing’s syndrome due to a thymic carcinoid tumour with periodic hormonogenesis. Periods of hormonal production averaged 27 days. Prior to bilateral adrenalectomy, mean (s.d) values of ACTH and cortisol were 202.1 (50.3) pg/ml and 46 (14.7) micrograms/dl, ACTH rising to 3996 +/- 425 pg/ml (P less than 0.01) and cortisol falling to 6.3 +/- 1.5 micrograms/dl (P less than 0.01) in the immediate postoperative period. During the late postoperative period (2-13 months following surgery) ACTH levels fell to 509.3 (123.8) pg/ml (P less than 0.01), but remaining even higher (P less than 0.01) than before adrenalectomy. The pattern of ACTH in the present case suggests the existence of a negative feedback exerted by the cortisol over tumoral ACTH." @default.
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- W2095632337 date "1987-10-01" @default.
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- W2095632337 title "Ectopic Cushing’s syndrome with periodic hormonogenesis--a case suggesting a pathogenetic mechanism" @default.
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- W2095632337 doi "https://doi.org/10.1136/pgmj.63.744.887" @default.
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