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- W2095644908 abstract "Fentanyl, a highly lipophilic drug (pka 7.7), is a common drug of abuse. The current standard techniques to detect fentanyl in urine have low recovery rates and poor sensitivity. We report a modified solvent extraction technique that can recover between 63 and 86% of the drug with a detection limit of 0.2 ng/10 ml of urine. In addition, we report the duration of urinary fentanyl excretion in 11 adolescent patients administered either low (< 10 mg/kg) or high (20-40 mg/kg) doses of fentanyl as part of anesthesia. The mean duration of urinary fentanyl excretion was similar in the two groups, with duration ranging from 1 to 5 days, and urine fentanyl concentration ranging from 0.1 ng to 10.3 ng/10 ml of urine." @default.
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- W2095644908 date "1989-01-01" @default.
- W2095644908 modified "2023-09-27" @default.
- W2095644908 title "A Method to increase recovery of fentanyl from urine" @default.
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- W2095644908 doi "https://doi.org/10.3109/15563658909038573" @default.
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