Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095656493> ?p ?o ?g. }
- W2095656493 endingPage "1534" @default.
- W2095656493 startingPage "1524" @default.
- W2095656493 abstract "Na+-dependent spikes initiate in the soma or axon hillock region and actively backpropagate into the dendritic arbor of many central neurons. Inward currents underlying spike discharge are offset by outward K+ currents that repolarize a spike and establish a refractory period to temporarily prevent spike discharge. We show in a sensory neuron that somatic and dendritic K+ channels differentially control burst discharge by regulating the extent to which backpropagating dendritic spikes can re-excite the soma. During repetitive discharge a progressive broadening of dendritic spikes promotes a dynamic increase in dendritic spike refractory period. A leaky integrate-and-fire model shows that spike bursts are terminated when a decreasing somatic interspike interval and an increasing dendritic spike refractory period synergistically act to block backpropagation. The time required for the somatic interspike interval to intersect with dendritic refractory period determines burst frequency, a time that is regulated by somatic and dendritic spike repolarization. Thus, K+ channels involved in spike repolarization can efficiently control the pattern of spike output by establishing a soma-dendritic interaction that invokes dynamic shifts in dendritic spike properties." @default.
- W2095656493 created "2016-06-24" @default.
- W2095656493 creator A5001340107 @default.
- W2095656493 creator A5004170163 @default.
- W2095656493 creator A5063019811 @default.
- W2095656493 creator A5068966129 @default.
- W2095656493 creator A5083381845 @default.
- W2095656493 date "2003-02-15" @default.
- W2095656493 modified "2023-10-18" @default.
- W2095656493 title "A Dynamic Dendritic Refractory Period Regulates Burst Discharge in the Electrosensory Lobe of Weakly Electric Fish" @default.
- W2095656493 cites W104516623 @default.
- W2095656493 cites W1500250295 @default.
- W2095656493 cites W1520854803 @default.
- W2095656493 cites W1531455680 @default.
- W2095656493 cites W1536319037 @default.
- W2095656493 cites W1549050411 @default.
- W2095656493 cites W1555091501 @default.
- W2095656493 cites W1675866414 @default.
- W2095656493 cites W1694767778 @default.
- W2095656493 cites W1747998245 @default.
- W2095656493 cites W1789081904 @default.
- W2095656493 cites W1850272931 @default.
- W2095656493 cites W1878366586 @default.
- W2095656493 cites W1906320646 @default.
- W2095656493 cites W1952486576 @default.
- W2095656493 cites W1967086564 @default.
- W2095656493 cites W1968945059 @default.
- W2095656493 cites W1979451628 @default.
- W2095656493 cites W1979598023 @default.
- W2095656493 cites W1991673195 @default.
- W2095656493 cites W1991742024 @default.
- W2095656493 cites W1997293666 @default.
- W2095656493 cites W2015791727 @default.
- W2095656493 cites W2017569276 @default.
- W2095656493 cites W2028226828 @default.
- W2095656493 cites W2044833738 @default.
- W2095656493 cites W2050566796 @default.
- W2095656493 cites W2055568369 @default.
- W2095656493 cites W2057426891 @default.
- W2095656493 cites W2081117504 @default.
- W2095656493 cites W2087417753 @default.
- W2095656493 cites W2090930028 @default.
- W2095656493 cites W2091828531 @default.
- W2095656493 cites W2099587101 @default.
- W2095656493 cites W2102706228 @default.
- W2095656493 cites W2112136490 @default.
- W2095656493 cites W2117829171 @default.
- W2095656493 cites W2118756527 @default.
- W2095656493 cites W2119760294 @default.
- W2095656493 cites W2124099961 @default.
- W2095656493 cites W2126468386 @default.
- W2095656493 cites W2126699012 @default.
- W2095656493 cites W2128362882 @default.
- W2095656493 cites W2132504829 @default.
- W2095656493 cites W2143885415 @default.
- W2095656493 cites W2144925492 @default.
- W2095656493 cites W2152419163 @default.
- W2095656493 cites W2165375369 @default.
- W2095656493 cites W2179502991 @default.
- W2095656493 cites W2186287000 @default.
- W2095656493 cites W2231571999 @default.
- W2095656493 doi "https://doi.org/10.1523/jneurosci.23-04-01524.2003" @default.
- W2095656493 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6742271" @default.
- W2095656493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12598641" @default.
- W2095656493 hasPublicationYear "2003" @default.
- W2095656493 type Work @default.
- W2095656493 sameAs 2095656493 @default.
- W2095656493 citedByCount "49" @default.
- W2095656493 countsByYear W20956564932012 @default.
- W2095656493 countsByYear W20956564932013 @default.
- W2095656493 countsByYear W20956564932014 @default.
- W2095656493 countsByYear W20956564932015 @default.
- W2095656493 countsByYear W20956564932016 @default.
- W2095656493 countsByYear W20956564932017 @default.
- W2095656493 countsByYear W20956564932018 @default.
- W2095656493 countsByYear W20956564932019 @default.
- W2095656493 countsByYear W20956564932020 @default.
- W2095656493 countsByYear W20956564932022 @default.
- W2095656493 crossrefType "journal-article" @default.
- W2095656493 hasAuthorship W2095656493A5001340107 @default.
- W2095656493 hasAuthorship W2095656493A5004170163 @default.
- W2095656493 hasAuthorship W2095656493A5063019811 @default.
- W2095656493 hasAuthorship W2095656493A5068966129 @default.
- W2095656493 hasAuthorship W2095656493A5083381845 @default.
- W2095656493 hasBestOaLocation W20956564931 @default.
- W2095656493 hasConcept C112592302 @default.
- W2095656493 hasConcept C115903868 @default.
- W2095656493 hasConcept C12554922 @default.
- W2095656493 hasConcept C146403970 @default.
- W2095656493 hasConcept C169760540 @default.
- W2095656493 hasConcept C17077164 @default.
- W2095656493 hasConcept C185263204 @default.
- W2095656493 hasConcept C195221683 @default.
- W2095656493 hasConcept C2779530196 @default.
- W2095656493 hasConcept C2779617337 @default.
- W2095656493 hasConcept C2781390188 @default.
- W2095656493 hasConcept C41008148 @default.
- W2095656493 hasConcept C42219234 @default.