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• W2095690420 endingPage "2564" @default.
• W2095690420 startingPage "2558" @default.
• W2095690420 abstract "Abstract The aim of the present study was to assess the potential use of biochemical markers and mentum deformities as indicators of long‐term exposure to lead (Pb) in Chironomus riparius larvae. To do this, the authors measured 3 biochemical markers (i.e., malondialdehyde level, metallothionein concentration, and energy reserve content) as well as larval growth and mentum deformities after 16‐d exposure to sediment containing Pb. The concentrations studied ranged from 3.5 mg/kg to 505.5 mg/kg dry weight. Despite the bioaccumulation of Pb in C. riparius bodies, frequencies of both mentum deformities and the dry weight were not significantly different between the control and stressed groups. On the contrary, Pb exposure caused a significant increase of both malondialdehyde level and metallothionein concentration. The increase of body Pb concentrations did not significantly modify body copper and zinc concentrations. Moreover, we observed a decrease of total lipid content and an increase of glycogen content as a function of a dose–response relationship, while no variation in protein concentrations was observed. Despite the adverse effects observed at the biochemical level, larval development was not affected. These results suggested that measurements of malondialdehyde level, metallothionein concentration, and energy reserve content can be used as relevant biomarkers of long‐term sublethal exposure to Pb in C. riparius larvae. Environ Toxicol Chem 2013;32:2558–2564. © 2013 SETAC" @default.
• W2095690420 created "2016-06-24" @default.
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• W2095690420 date "2013-08-26" @default.
• W2095690420 modified "2023-10-16" @default.
• W2095690420 title "Biochemical and morphological responses in<i>Chironomus riparius</i>(Diptera, Chironomidae) larvae exposed to lead-spiked sediment" @default.
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• W2095690420 doi "https://doi.org/10.1002/etc.2336" @default.
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