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- W2095690884 abstract "Glucocorticoid metabolites enter the aquatic environment via mammalian excrements. Molecular structures of their C19O3 metabolites strongly resemble the major fish androgen 11-ketotestosterone. Therefore, we tested the hypothesis that the cortisol metabolite 5α-androstan-3,11,17-trione acts similarly to 11-ketotestosterone by employing a fish screening assay for endocrine-active substances. After 21 d, both 11-oxygenated compounds had masculinized sex characteristics of the anal fin in female medaka in a dose-dependent manner. Environ. Toxicol. Chem. 2010;29:1613–1620. © 2010 SETAC" @default.
- W2095690884 created "2016-06-24" @default.
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- W2095690884 date "2010-03-30" @default.
- W2095690884 modified "2023-10-06" @default.
- W2095690884 title "Mammalian glucocorticoid metabolites act as androgenic endocrine disruptors in the medaka (Oryzias latipes)" @default.
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- W2095690884 doi "https://doi.org/10.1002/etc.176" @default.
- W2095690884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20821612" @default.
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