FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095698859> ?p ?o ?g. }

• W2095698859 abstract "Japanese encephalitis virus (JEV) is an arthropod-borne virus causing serious public health issues in Asia. JEV consists of five genotypes and recent studies have shown the emergence of JEV genotype I (GI) and its replacement of genotype III (GIII). Using an archival JEV collection, we investigated the molecular evolution of JEV in Vietnam over the last 48 years (1964-2012) in humans, mosquitoes, and pigs, within the global context.The nine JEV isolates from humans, pigs, and mosquitoes sequenced in this study and 29 sequences available in GenBank were used to analyze the envelope (E) protein of the Vietnamese JEVs. A collection of 225 cerebrospinal fluid specimens from patients with suspected Japanese encephalitis (JE) was also tested and genotyped with real-time RT-PCR.The 38 E genes identified with sequencing and nine Vietnamese JEV strains genotyped with real-time RT-PCR, belonging to two lineages, evolved in accordance with those in the rest of the world. The first GIII strain was detected in humans in Vietnam in 1964, and in mosquitoes in 1979, whereas GI strains were first detected in humans and mosquitoes in 1990 and 1994, respectively. After 2004, GI was the only genotype detected in Vietnam, demonstrating that the GIIII strains had been displaced by GI strains. Five haplotypes were identified in the Vietnamese JEVs, with SKSS predominant. The S123N and S123R substitutions in the E protein were already present in the Vietnamese JEVs.This study describes the long evolutionary history of JEV in Vietnam over 34 years, which correlates well with the global evolution of JEV. The Vietnamese GIII strains have been replaced by GI strains in mosquitoes, pigs, and humans. The predominant haplotypes of the Vietnamese strains support this genotype displacement in Vietnam. Further surveillance is required to confirm the disappearance of the GIII strains in nature and the emergence of new pathogens causing encephalitis in Vietnam, after the long-term use of JEV vaccines in that country." @default.
• W2095698859 created "2016-06-24" @default.
• W2095698859 creator A5012677279 @default.
• W2095698859 creator A5030352792 @default.
• W2095698859 creator A5064556643 @default.
• W2095698859 creator A5075683698 @default.
• W2095698859 creator A5087522888 @default.
• W2095698859 date "2015-04-01" @default.
• W2095698859 modified "2023-09-26" @default.
• W2095698859 title "Molecular epidemiology of Japanese encephalitis in northern Vietnam, 1964–2011: genotype replacement" @default.
• W2095698859 cites W1841110600 @default.
• W2095698859 cites W1949052939 @default.
• W2095698859 cites W1966979525 @default.
• W2095698859 cites W1979471211 @default.
• W2095698859 cites W1979987816 @default.
• W2095698859 cites W2000946204 @default.
• W2095698859 cites W2034318935 @default.
• W2095698859 cites W2047313387 @default.
• W2095698859 cites W2048515798 @default.
• W2095698859 cites W2048992782 @default.
• W2095698859 cites W2054507269 @default.
• W2095698859 cites W2060674036 @default.
• W2095698859 cites W2097706568 @default.
• W2095698859 cites W2106717400 @default.
• W2095698859 cites W2106882534 @default.
• W2095698859 cites W2107351495 @default.
• W2095698859 cites W2110721832 @default.
• W2095698859 cites W2114817968 @default.
• W2095698859 cites W2125365106 @default.
• W2095698859 cites W2136615622 @default.
• W2095698859 cites W2147060276 @default.
• W2095698859 cites W2150029699 @default.
• W2095698859 cites W2151368749 @default.
• W2095698859 cites W2152207030 @default.
• W2095698859 cites W2153309140 @default.
• W2095698859 cites W2153988692 @default.
• W2095698859 cites W2156320128 @default.
• W2095698859 cites W2166305421 @default.
• W2095698859 cites W2367182359 @default.
• W2095698859 cites W2412486856 @default.
• W2095698859 cites W2416202249 @default.
• W2095698859 doi "https://doi.org/10.1186/s12985-015-0278-4" @default.
• W2095698859 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4417254" @default.
• W2095698859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25889499" @default.
• W2095698859 hasPublicationYear "2015" @default.
• W2095698859 type Work @default.
• W2095698859 sameAs 2095698859 @default.
• W2095698859 citedByCount "31" @default.
• W2095698859 countsByYear W20956988592015 @default.
• W2095698859 countsByYear W20956988592016 @default.
• W2095698859 countsByYear W20956988592017 @default.
• W2095698859 countsByYear W20956988592018 @default.
• W2095698859 countsByYear W20956988592019 @default.
• W2095698859 countsByYear W20956988592020 @default.
• W2095698859 countsByYear W20956988592021 @default.
• W2095698859 countsByYear W20956988592022 @default.
• W2095698859 crossrefType "journal-article" @default.
• W2095698859 hasAuthorship W2095698859A5012677279 @default.
• W2095698859 hasAuthorship W2095698859A5030352792 @default.
• W2095698859 hasAuthorship W2095698859A5064556643 @default.
• W2095698859 hasAuthorship W2095698859A5075683698 @default.
• W2095698859 hasAuthorship W2095698859A5087522888 @default.
• W2095698859 hasBestOaLocation W20956988591 @default.
• W2095698859 hasConcept C103621254 @default.
• W2095698859 hasConcept C104317684 @default.
• W2095698859 hasConcept C135763542 @default.
• W2095698859 hasConcept C138885662 @default.
• W2095698859 hasConcept C151730666 @default.
• W2095698859 hasConcept C159047783 @default.
• W2095698859 hasConcept C2522874641 @default.
• W2095698859 hasConcept C2777888124 @default.
• W2095698859 hasConcept C2778889330 @default.
• W2095698859 hasConcept C2779141303 @default.
• W2095698859 hasConcept C2779343474 @default.
• W2095698859 hasConcept C41895202 @default.
• W2095698859 hasConcept C54355233 @default.
• W2095698859 hasConcept C79029880 @default.
• W2095698859 hasConcept C83455156 @default.
• W2095698859 hasConcept C86803240 @default.
• W2095698859 hasConcept C97669555 @default.
• W2095698859 hasConceptScore W2095698859C103621254 @default.
• W2095698859 hasConceptScore W2095698859C104317684 @default.
• W2095698859 hasConceptScore W2095698859C135763542 @default.
• W2095698859 hasConceptScore W2095698859C138885662 @default.
• W2095698859 hasConceptScore W2095698859C151730666 @default.
• W2095698859 hasConceptScore W2095698859C159047783 @default.
• W2095698859 hasConceptScore W2095698859C2522874641 @default.
• W2095698859 hasConceptScore W2095698859C2777888124 @default.
• W2095698859 hasConceptScore W2095698859C2778889330 @default.
• W2095698859 hasConceptScore W2095698859C2779141303 @default.
• W2095698859 hasConceptScore W2095698859C2779343474 @default.
• W2095698859 hasConceptScore W2095698859C41895202 @default.
• W2095698859 hasConceptScore W2095698859C54355233 @default.
• W2095698859 hasConceptScore W2095698859C79029880 @default.
• W2095698859 hasConceptScore W2095698859C83455156 @default.
• W2095698859 hasConceptScore W2095698859C86803240 @default.
• W2095698859 hasConceptScore W2095698859C97669555 @default.
• W2095698859 hasIssue "1" @default.
• W2095698859 hasLocation W20956988591 @default.
• W2095698859 hasLocation W20956988592 @default.

• next