FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095758301> ?p ?o ?g. }

• W2095758301 endingPage "270" @default.
• W2095758301 startingPage "263" @default.
• W2095758301 abstract "We have previously demonstrated a dose response relationship in Hodgkin's disease for the combination of BCNU, VP16, Ara C and Melphalan, with the superior efficacy of the BEAM regimen requiring haemopoietic support, compared with miniBEAM. To further exploit this, we have attempted to escalate the VP16 dose in BEAM. The standard etoposide dose is 200 mg/m2 IV for four days. Thirty seven patients with refractory lymphoma received 400 mg/m2/day of etoposide, and 13 patients 600 mg/m2/day, in addition to BCNU, cytarabine, and melphalan. Toxicity and outcome parameters were compared in the preceding 40 patients, who received 200 mg/m2/day etoposide. The toxic mortality with 400 mg/m2/day of etoposide (3%) was identical to that for the standard BEAM regimen (5%). Two procedure related deaths occurred in the highest VP16 dose group (15%). The morbidity of the lower etoposide dose regimens was comparable, but 600 mg/m2/day induced significantly greater gastrointestinal toxicity. Twelve of the 13 patients receiving this dose suffered grade II-IV mucositis, with stomatitis, dysphagia and prolonged diarrhoea; 5 haemodynamically significant gastrointestinal haemorrhage, and 1 fatal toxic colitis. Granulocyte colony stimulating factor did not influence the nonhaematological toxicity. The three month response rates were similar (91%) in all dose cohorts. The maximum tolerable etoposide dose within the BEAM regimen is thus 400 mg/m2 for four days." @default.
• W2095758301 created "2016-06-24" @default.
• W2095758301 creator A5005708709 @default.
• W2095758301 creator A5027158912 @default.
• W2095758301 creator A5048056597 @default.
• W2095758301 creator A5061507542 @default.
• W2095758301 date "1995-01-01" @default.
• W2095758301 modified "2023-09-26" @default.
• W2095758301 title "Dose Intensification of Etoposide in the BEAM ABMT Protocol for Malignant Lymphoma" @default.
• W2095758301 cites W118673291 @default.
• W2095758301 cites W1808994586 @default.
• W2095758301 cites W1834664850 @default.
• W2095758301 cites W1841420516 @default.
• W2095758301 cites W1846648891 @default.
• W2095758301 cites W1856398768 @default.
• W2095758301 cites W1881397173 @default.
• W2095758301 cites W1888835857 @default.
• W2095758301 cites W1911320760 @default.
• W2095758301 cites W1954992673 @default.
• W2095758301 cites W1971099109 @default.
• W2095758301 cites W1977480003 @default.
• W2095758301 cites W1983798271 @default.
• W2095758301 cites W1998440071 @default.
• W2095758301 cites W2017416417 @default.
• W2095758301 cites W2041629407 @default.
• W2095758301 cites W2045767625 @default.
• W2095758301 cites W2073639129 @default.
• W2095758301 cites W2075898541 @default.
• W2095758301 cites W2092015388 @default.
• W2095758301 cites W2141082026 @default.
• W2095758301 cites W2165308914 @default.
• W2095758301 cites W2180991615 @default.
• W2095758301 cites W2185768010 @default.
• W2095758301 cites W2254324119 @default.
• W2095758301 cites W2259377666 @default.
• W2095758301 cites W2273350722 @default.
• W2095758301 cites W2318772898 @default.
• W2095758301 cites W3024436806 @default.
• W2095758301 cites W4233701056 @default.
• W2095758301 cites W94237140 @default.
• W2095758301 doi "https://doi.org/10.3109/10428199509056831" @default.
• W2095758301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8580795" @default.
• W2095758301 hasPublicationYear "1995" @default.
• W2095758301 type Work @default.
• W2095758301 sameAs 2095758301 @default.
• W2095758301 citedByCount "24" @default.
• W2095758301 countsByYear W20957583012016 @default.
• W2095758301 countsByYear W20957583012017 @default.
• W2095758301 countsByYear W20957583012019 @default.
• W2095758301 countsByYear W20957583012020 @default.
• W2095758301 countsByYear W20957583012021 @default.
• W2095758301 countsByYear W20957583012023 @default.
• W2095758301 crossrefType "journal-article" @default.
• W2095758301 hasAuthorship W2095758301A5005708709 @default.
• W2095758301 hasAuthorship W2095758301A5027158912 @default.
• W2095758301 hasAuthorship W2095758301A5048056597 @default.
• W2095758301 hasAuthorship W2095758301A5061507542 @default.
• W2095758301 hasConcept C126322002 @default.
• W2095758301 hasConcept C141071460 @default.
• W2095758301 hasConcept C2776694085 @default.
• W2095758301 hasConcept C2778041864 @default.
• W2095758301 hasConcept C2778119113 @default.
• W2095758301 hasConcept C2778496288 @default.
• W2095758301 hasConcept C2778684742 @default.
• W2095758301 hasConcept C2781413609 @default.
• W2095758301 hasConcept C29730261 @default.
• W2095758301 hasConcept C71924100 @default.
• W2095758301 hasConcept C90924648 @default.
• W2095758301 hasConceptScore W2095758301C126322002 @default.
• W2095758301 hasConceptScore W2095758301C141071460 @default.
• W2095758301 hasConceptScore W2095758301C2776694085 @default.
• W2095758301 hasConceptScore W2095758301C2778041864 @default.
• W2095758301 hasConceptScore W2095758301C2778119113 @default.
• W2095758301 hasConceptScore W2095758301C2778496288 @default.
• W2095758301 hasConceptScore W2095758301C2778684742 @default.
• W2095758301 hasConceptScore W2095758301C2781413609 @default.
• W2095758301 hasConceptScore W2095758301C29730261 @default.
• W2095758301 hasConceptScore W2095758301C71924100 @default.
• W2095758301 hasConceptScore W2095758301C90924648 @default.
• W2095758301 hasIssue "3-4" @default.
• W2095758301 hasLocation W20957583011 @default.
• W2095758301 hasLocation W20957583012 @default.
• W2095758301 hasOpenAccess W2095758301 @default.
• W2095758301 hasPrimaryLocation W20957583011 @default.
• W2095758301 hasRelatedWork W1999938278 @default.
• W2095758301 hasRelatedWork W2057456103 @default.
• W2095758301 hasRelatedWork W2095758301 @default.
• W2095758301 hasRelatedWork W2163996738 @default.
• W2095758301 hasRelatedWork W2299494654 @default.
• W2095758301 hasRelatedWork W2589677112 @default.
• W2095758301 hasRelatedWork W2949760313 @default.
• W2095758301 hasRelatedWork W3156198912 @default.
• W2095758301 hasRelatedWork W4382361983 @default.
• W2095758301 hasRelatedWork W4386116444 @default.
• W2095758301 hasVolume "17" @default.
• W2095758301 isParatext "false" @default.
• W2095758301 isRetracted "false" @default.
• W2095758301 magId "2095758301" @default.

• next