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- W2095790066 abstract "Six hundred postmortem and emergency room urine analysis for benzodiazepines were performed by both the EMIT-dau Benzodiazepine Metabolite Assay (EMIT) and thin layer chromatography (TLC). Benzodiazepine drugs or metabolites were detected in 90 urines by TLC and 84 urines by EMIT. Of th six apparent false negative EMIT analysis, three were due to high edogeneous lysozyme activity and three were due to the greater sensitivity of TLC (0.1 mg/L) versus EMIT (0.5 mg/L). The EMIT assay sensitivity for four benzodiazepine drugs and five of their major uninary metabolites was determined. Benzodiazepines unsubstituted at the N-1 position displayed the greatest sensitivity by EMIT assay, 0.5 mg/L. Twenty-six nonbenzodiazepine drugs or drug metabolites commonly encountered in urine drug screening, failed to produce significant false positive or false negative results with the EMIT benzodiazepine assay." @default.
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- W2095790066 date "1981-07-01" @default.
- W2095790066 modified "2023-10-07" @default.
- W2095790066 title "An Evaluation of EMIT® Benzodiazepine Metabolite Assay for Urine Drug Screening" @default.
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- W2095790066 doi "https://doi.org/10.1093/jat/5.4.174" @default.
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