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- W2095795961 abstract "Editorial Notes1 June 1968Familial Renal Tubular AcidosisVARDAMAN M. BUCKALEW JR., M.D.VARDAMAN M. BUCKALEW JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-68-6-1367 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is now well-established that the syndrome of renal tubular acidosis (RTA), in which the primary defect is an inability to lower urinary pH normally, occurs as a familial disease in a small percentage of cases. However, the mode of transmission is not entirely clear. In a recent review, Seldin and Wilson (1) summarized the evidence in 14 families suggesting that familial RTA is due to an autosomal dominant gene. The strongest evidence favoring this view is found in the two families originally reported by Pitts, Schulte, and Smith (2) and subsequently by Randall and Taggart (3) and by Schreiner,...References1. SELDINWILSON DWJD: Renal tubular acidosis, in The Metabolic Basis of Inherited Disease, 2nd ed., edited by STANBURY, J. B., WYNGAARDEN, J. B., FREDRICKSON, D. S., McGraw-Hill Book Co., Inc., New York, 1966, p. 1230. Google Scholar2. PITTSSCHULTESMITH HHJWDR: Nephrocalcinosis in a father and three children. J. Urol. 73: 208, 1955. CrossrefMedlineGoogle Scholar3. RANDALLTAGGART REWH: Familial renal tubular acidosis. Ann. Intern. Med. 54: 1108, 1961. LinkGoogle Scholar4. SCHREINERSMITHKYLE GELHLH: Renal hyperchloremic acidosis. Amer. J. Med. 15: 122, 1953. CrossrefMedlineGoogle Scholar5. RANDALL RE: Familial renal tubular acidosis revisited (letters and comments). Ann. Intern. Med. 66: 1024, 1967. LinkGoogle Scholar6. ELKINTONMCCURDYBUCKALEW JRDKVM: Hydrogen ion and the kidney, in Renal Disease, 2nd ed., edited by BLACK, D. A. K., Blackwell Scientific Publications Ltd., Oxford, 1967, p. 110. Google Scholar7. BUCKALEWMCCURDYLUDWIGCHAYKINELKINTON VMDKGDLBJR: Incomplete renal tubular acidosis. Physiological studies in three patients with a defect in lowering urinary pH. Amer. J. Med.: in press, 1968. MedlineGoogle Scholar8. KUHLENCORDTLENZSEEMANNZUKSCHWERDT FWNL: Renal tubular acidosis and bilateral nephrocalcinosis in uniovular twins. German Med. Monthly 12: 565, 1967. MedlineGoogle Scholar9. WRONGDAVIES OHE: The excretion of acid in renal disease. Quart. J. Med. 28: 259, 1959. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine Emory University School of Medicine Atlanta, Ga. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 June 1968Volume 68, Issue 6Page: 1367-1368KeywordsRenal diseases Issue Published: 1 June 1968 PDF downloadLoading ..." @default.
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