Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095805440> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2095805440 endingPage "2485" @default.
- W2095805440 startingPage "2480" @default.
- W2095805440 abstract "A growing number of the elements identified in intracellular signaling events that affect cell growth and transformation are proteins that physically interact with each other via domains or specifically recognized amino acid sequences. Some of these intracellular protein–protein interactions are attractive targets for anticancer targeted therapy, but progress in this field has been compromised by the paucity of compounds with suitable biological profiles and pharmacological properties. This Letter covers salient achievements in the identification and development of inhibitors of the p53–hdm2 protein–protein interaction, and highlights different screening techniques and structure-based design approaches that may be brought to bear on the discovery and development of inhibitors of other therapeutically relevant intracellular protein–protein interactions." @default.
- W2095805440 created "2016-06-24" @default.
- W2095805440 creator A5006321055 @default.
- W2095805440 creator A5060009480 @default.
- W2095805440 date "2013-05-01" @default.
- W2095805440 modified "2023-10-18" @default.
- W2095805440 title "Inhibitors of the p53/hdm2 protein–protein interaction—path to the clinic" @default.
- W2095805440 cites W1976261939 @default.
- W2095805440 cites W1992489244 @default.
- W2095805440 cites W1998767804 @default.
- W2095805440 cites W1999978441 @default.
- W2095805440 cites W2008845432 @default.
- W2095805440 cites W2008887283 @default.
- W2095805440 cites W2011588098 @default.
- W2095805440 cites W2014583828 @default.
- W2095805440 cites W2022416218 @default.
- W2095805440 cites W2022872622 @default.
- W2095805440 cites W2035177083 @default.
- W2095805440 cites W2040576705 @default.
- W2095805440 cites W2050214049 @default.
- W2095805440 cites W2054074966 @default.
- W2095805440 cites W2064330613 @default.
- W2095805440 cites W2067990107 @default.
- W2095805440 cites W2070932122 @default.
- W2095805440 cites W2079945282 @default.
- W2095805440 cites W2082642762 @default.
- W2095805440 cites W2084317612 @default.
- W2095805440 cites W2092510959 @default.
- W2095805440 cites W2097933346 @default.
- W2095805440 cites W2099293745 @default.
- W2095805440 cites W2103199808 @default.
- W2095805440 cites W2116416768 @default.
- W2095805440 cites W2126708001 @default.
- W2095805440 cites W2127506367 @default.
- W2095805440 cites W2144119251 @default.
- W2095805440 cites W2155782154 @default.
- W2095805440 cites W2155906069 @default.
- W2095805440 cites W2156157326 @default.
- W2095805440 cites W2171033030 @default.
- W2095805440 cites W2326231992 @default.
- W2095805440 cites W2330719680 @default.
- W2095805440 cites W40735305 @default.
- W2095805440 doi "https://doi.org/10.1016/j.bmcl.2013.03.034" @default.
- W2095805440 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23541651" @default.
- W2095805440 hasPublicationYear "2013" @default.
- W2095805440 type Work @default.
- W2095805440 sameAs 2095805440 @default.
- W2095805440 citedByCount "71" @default.
- W2095805440 countsByYear W20958054402013 @default.
- W2095805440 countsByYear W20958054402014 @default.
- W2095805440 countsByYear W20958054402015 @default.
- W2095805440 countsByYear W20958054402016 @default.
- W2095805440 countsByYear W20958054402017 @default.
- W2095805440 countsByYear W20958054402018 @default.
- W2095805440 countsByYear W20958054402019 @default.
- W2095805440 countsByYear W20958054402020 @default.
- W2095805440 countsByYear W20958054402022 @default.
- W2095805440 countsByYear W20958054402023 @default.
- W2095805440 crossrefType "journal-article" @default.
- W2095805440 hasAuthorship W2095805440A5006321055 @default.
- W2095805440 hasAuthorship W2095805440A5060009480 @default.
- W2095805440 hasBestOaLocation W20958054401 @default.
- W2095805440 hasConcept C11804247 @default.
- W2095805440 hasConcept C185592680 @default.
- W2095805440 hasConcept C55493867 @default.
- W2095805440 hasConcept C70721500 @default.
- W2095805440 hasConcept C79879829 @default.
- W2095805440 hasConcept C86803240 @default.
- W2095805440 hasConcept C95444343 @default.
- W2095805440 hasConceptScore W2095805440C11804247 @default.
- W2095805440 hasConceptScore W2095805440C185592680 @default.
- W2095805440 hasConceptScore W2095805440C55493867 @default.
- W2095805440 hasConceptScore W2095805440C70721500 @default.
- W2095805440 hasConceptScore W2095805440C79879829 @default.
- W2095805440 hasConceptScore W2095805440C86803240 @default.
- W2095805440 hasConceptScore W2095805440C95444343 @default.
- W2095805440 hasIssue "9" @default.
- W2095805440 hasLocation W20958054401 @default.
- W2095805440 hasLocation W20958054402 @default.
- W2095805440 hasOpenAccess W2095805440 @default.
- W2095805440 hasPrimaryLocation W20958054401 @default.
- W2095805440 hasRelatedWork W1549554643 @default.
- W2095805440 hasRelatedWork W2026264997 @default.
- W2095805440 hasRelatedWork W2065261206 @default.
- W2095805440 hasRelatedWork W2153616445 @default.
- W2095805440 hasRelatedWork W2775117660 @default.
- W2095805440 hasRelatedWork W2889105623 @default.
- W2095805440 hasRelatedWork W3125436686 @default.
- W2095805440 hasRelatedWork W3180324226 @default.
- W2095805440 hasRelatedWork W3215880097 @default.
- W2095805440 hasRelatedWork W4367846269 @default.
- W2095805440 hasVolume "23" @default.
- W2095805440 isParatext "false" @default.
- W2095805440 isRetracted "false" @default.
- W2095805440 magId "2095805440" @default.
- W2095805440 workType "article" @default.