FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095828496> ?p ?o ?g. }

• W2095828496 endingPage "32" @default.
• W2095828496 startingPage "26" @default.
• W2095828496 abstract "Non-small-cell lung cancer (NSCLC) is frequently characterized by metastases to bone. Bisphosphonates have demonstrated efficacy in reducing the risk of skeletal-related events in cancer patients with bone metastases, including those with NSCLC. Zoledronic acid (ZA) is one of the most potent bisphosphonates and is approved for the first-line treatment of patients with multiple myeloma and bone metastases from solid tumors. Recent preclinical and clinical data suggest that ZA may also have direct and indirect anticancer effects. Several preclinical studies have provided insight into the potential mechanisms responsible for the anticancer activity of ZA, including inhibiting farnesyl pyrophosphate or geranylgeranyl pyrophosphate and activation of immune-mediated anticancer response by γδ T cells. In patients with NSCLC, ZA has been shown to reduce vascular endothelial growth factor levels with a direct correlation to clinical response. Clinical studies in this setting have shown that ZA may also provide a survival benefit and prolong time to progression. Ongoing studies are evaluating the efficacy of ZA for anticancer activity and prevention of bone metastases. Bisphosphonates, particularly ZA, are generally well tolerated and may likely offer an adjunct therapeutic option for patients with NSCLC." @default.
• W2095828496 created "2016-06-24" @default.
• W2095828496 creator A5000862048 @default.
• W2095828496 creator A5006757571 @default.
• W2095828496 creator A5064127817 @default.
• W2095828496 date "2011-01-01" @default.
• W2095828496 modified "2023-09-26" @default.
• W2095828496 title "The Potential Application of Zoledronic Acid as Anticancer Therapy in Patients With Non–Small-Cell Lung Cancer" @default.
• W2095828496 cites W1967568153 @default.
• W2095828496 cites W1984675066 @default.
• W2095828496 cites W1989664451 @default.
• W2095828496 cites W1995615104 @default.
• W2095828496 cites W1996589664 @default.
• W2095828496 cites W2002094338 @default.
• W2095828496 cites W2013571231 @default.
• W2095828496 cites W2028243830 @default.
• W2095828496 cites W2038884712 @default.
• W2095828496 cites W2047729322 @default.
• W2095828496 cites W2061634743 @default.
• W2095828496 cites W2065674163 @default.
• W2095828496 cites W2068530253 @default.
• W2095828496 cites W2076370157 @default.
• W2095828496 cites W2079449116 @default.
• W2095828496 cites W2084651782 @default.
• W2095828496 cites W2087262736 @default.
• W2095828496 cites W2087324367 @default.
• W2095828496 cites W2092868870 @default.
• W2095828496 cites W2093605516 @default.
• W2095828496 cites W2095154871 @default.
• W2095828496 cites W2101995865 @default.
• W2095828496 cites W2103011422 @default.
• W2095828496 cites W2119565876 @default.
• W2095828496 cites W2122972229 @default.
• W2095828496 cites W2138767612 @default.
• W2095828496 cites W2144860907 @default.
• W2095828496 cites W2148096512 @default.
• W2095828496 cites W2149221991 @default.
• W2095828496 cites W2149783480 @default.
• W2095828496 cites W2150904792 @default.
• W2095828496 cites W2152409486 @default.
• W2095828496 cites W2157839113 @default.
• W2095828496 cites W2167840876 @default.
• W2095828496 cites W2171178563 @default.
• W2095828496 cites W2565833074 @default.
• W2095828496 doi "https://doi.org/10.3816/clc.2011.n.003" @default.
• W2095828496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21273176" @default.
• W2095828496 hasPublicationYear "2011" @default.
• W2095828496 type Work @default.
• W2095828496 sameAs 2095828496 @default.
• W2095828496 citedByCount "16" @default.
• W2095828496 countsByYear W20958284962012 @default.
• W2095828496 countsByYear W20958284962013 @default.
• W2095828496 countsByYear W20958284962014 @default.
• W2095828496 countsByYear W20958284962015 @default.
• W2095828496 countsByYear W20958284962016 @default.
• W2095828496 countsByYear W20958284962017 @default.
• W2095828496 countsByYear W20958284962019 @default.
• W2095828496 countsByYear W20958284962020 @default.
• W2095828496 crossrefType "journal-article" @default.
• W2095828496 hasAuthorship W2095828496A5000862048 @default.
• W2095828496 hasAuthorship W2095828496A5006757571 @default.
• W2095828496 hasAuthorship W2095828496A5064127817 @default.
• W2095828496 hasConcept C121608353 @default.
• W2095828496 hasConcept C126322002 @default.
• W2095828496 hasConcept C143998085 @default.
• W2095828496 hasConcept C181199279 @default.
• W2095828496 hasConcept C185592680 @default.
• W2095828496 hasConcept C2776256026 @default.
• W2095828496 hasConcept C2776326535 @default.
• W2095828496 hasConcept C2776364478 @default.
• W2095828496 hasConcept C2776990775 @default.
• W2095828496 hasConcept C2778827360 @default.
• W2095828496 hasConcept C502942594 @default.
• W2095828496 hasConcept C553450214 @default.
• W2095828496 hasConcept C55493867 @default.
• W2095828496 hasConcept C57790582 @default.
• W2095828496 hasConcept C71924100 @default.
• W2095828496 hasConceptScore W2095828496C121608353 @default.
• W2095828496 hasConceptScore W2095828496C126322002 @default.
• W2095828496 hasConceptScore W2095828496C143998085 @default.
• W2095828496 hasConceptScore W2095828496C181199279 @default.
• W2095828496 hasConceptScore W2095828496C185592680 @default.
• W2095828496 hasConceptScore W2095828496C2776256026 @default.
• W2095828496 hasConceptScore W2095828496C2776326535 @default.
• W2095828496 hasConceptScore W2095828496C2776364478 @default.
• W2095828496 hasConceptScore W2095828496C2776990775 @default.
• W2095828496 hasConceptScore W2095828496C2778827360 @default.
• W2095828496 hasConceptScore W2095828496C502942594 @default.
• W2095828496 hasConceptScore W2095828496C553450214 @default.
• W2095828496 hasConceptScore W2095828496C55493867 @default.
• W2095828496 hasConceptScore W2095828496C57790582 @default.
• W2095828496 hasConceptScore W2095828496C71924100 @default.
• W2095828496 hasIssue "1" @default.
• W2095828496 hasLocation W20958284961 @default.
• W2095828496 hasLocation W20958284962 @default.
• W2095828496 hasOpenAccess W2095828496 @default.
• W2095828496 hasPrimaryLocation W20958284961 @default.
• W2095828496 hasRelatedWork W1561111810 @default.

• next