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- W2095861937 abstract "Proteome research aims to unravel the biological complexity encoded by the genome. Due to the complexity of higher eukaryotic cells, single-step characterization of a proteome is likely to be difficult to achieve. However, advantage can be taken of the macromolecular architecture of a cell, e.g., subcellular compartments, organelles, macromolecular structures and multiprotein complexes, to establish subcellular proteomes. This review highlights recent developments in this area of proteomics, namely the establishment of two-dimensional electrophoresis (2-DE) reference maps of subcellular compartments and organelles as well as the characterization of macromolecular structures and multiprotein complexes using a proteomics approach." @default.
- W2095861937 created "2016-06-24" @default.
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- W2095861937 date "2000-10-01" @default.
- W2095861937 modified "2023-10-18" @default.
- W2095861937 title "Proteomics meets cell biology: The establishment of subcellular proteomes" @default.
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- W2095861937 doi "https://doi.org/10.1002/1522-2683(20001001)21:16<3369::aid-elps3369>3.0.co;2-7" @default.
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