FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095996735> ?p ?o ?g. }

• W2095996735 endingPage "1074" @default.
• W2095996735 startingPage "1066" @default.
• W2095996735 abstract "In this study, we hypothesized that epigallocatechin gallate (EGCG) would suppress inflammation in the pancreas, and thus, we investigated the effects that EGCG administration had in the pancreas of rats fed a high-fat diet (HFD). To test our hypothesis, 30 male Sprague-Dawley rats were divided into 2 groups: normal diet (control) group and HFD group. When there was a significant difference in body weight between the 2 groups (P < .05), the HFD group was further divided into 2 subgroups: the HFD group (HFD, n = 10, 16 weeks) and the EGCG group (HFD + 3.2 g/kg EGCG, n = 10, 16 weeks). Metabolite levels and the expression of inflammatory markers (tumor necrosis factor alpha [TNF-α], interleukin 6 [IL-6], and toll-like receptor 4) were measured using standard biochemical techniques. Insulin secretion and pancreatic histology were also evaluated. Epigallocatechin gallate significantly decreased fasting insulin levels as well as the homeostasis model assessment–insulin resistance index. In the HFD group, the average glucose infusion rate and the TNF-α and IL-6 levels increased, whereas toll-like receptor 4 and TNF receptor-associated factor-6 did not. A pathologic analysis of pancreatic tissue revealed an increase in inflammatory TNF-α and infiltrating CD68+ macrophages in the islets of the HFD rats, but rarely is this observed in the in the HFD + EGCG rats. Overall, these data suggest that EGCG suppresses inflammation, partially reverses metabolic abnormalities, and ultimately increases insulin sensitivity in the pancreas of HFD rats." @default.
• W2095996735 created "2016-06-24" @default.
• W2095996735 creator A5003542900 @default.
• W2095996735 creator A5016369696 @default.
• W2095996735 creator A5019685555 @default.
• W2095996735 creator A5055675142 @default.
• W2095996735 creator A5058070060 @default.
• W2095996735 creator A5078643287 @default.
• W2095996735 creator A5080470851 @default.
• W2095996735 date "2014-12-01" @default.
• W2095996735 modified "2023-10-06" @default.
• W2095996735 title "Epigallocatechin gallate prevents inflammation by reducing macrophage infiltration and inhibiting tumor necrosis factor-α signaling in the pancreas of rats on a high-fat diet" @default.
• W2095996735 cites W1979598489 @default.
• W2095996735 cites W1980152778 @default.
• W2095996735 cites W1982328176 @default.
• W2095996735 cites W1984245055 @default.
• W2095996735 cites W1985399572 @default.
• W2095996735 cites W1988327539 @default.
• W2095996735 cites W1991300803 @default.
• W2095996735 cites W1999162212 @default.
• W2095996735 cites W2003292720 @default.
• W2095996735 cites W2003965937 @default.
• W2095996735 cites W2004969093 @default.
• W2095996735 cites W2012506647 @default.
• W2095996735 cites W2012640938 @default.
• W2095996735 cites W2023174389 @default.
• W2095996735 cites W2025791042 @default.
• W2095996735 cites W2028320377 @default.
• W2095996735 cites W2028733244 @default.
• W2095996735 cites W2037884311 @default.
• W2095996735 cites W2044277129 @default.
• W2095996735 cites W2046388378 @default.
• W2095996735 cites W2056499167 @default.
• W2095996735 cites W2058857909 @default.
• W2095996735 cites W2059935604 @default.
• W2095996735 cites W2064207652 @default.
• W2095996735 cites W2068425317 @default.
• W2095996735 cites W2069746141 @default.
• W2095996735 cites W2074234588 @default.
• W2095996735 cites W2075380466 @default.
• W2095996735 cites W2076998598 @default.
• W2095996735 cites W2083666530 @default.
• W2095996735 cites W2089457363 @default.
• W2095996735 cites W2089770443 @default.
• W2095996735 cites W2097563901 @default.
• W2095996735 cites W2098873988 @default.
• W2095996735 cites W2101328621 @default.
• W2095996735 cites W2102373269 @default.
• W2095996735 cites W2117169050 @default.
• W2095996735 cites W2120071870 @default.
• W2095996735 cites W2120255817 @default.
• W2095996735 cites W2123259868 @default.
• W2095996735 cites W2130213180 @default.
• W2095996735 cites W2131701710 @default.
• W2095996735 cites W2134133526 @default.
• W2095996735 cites W2135794002 @default.
• W2095996735 cites W2137098883 @default.
• W2095996735 cites W2137274603 @default.
• W2095996735 cites W2140573009 @default.
• W2095996735 cites W2143014690 @default.
• W2095996735 cites W2146561547 @default.
• W2095996735 cites W2152429535 @default.
• W2095996735 cites W2152842365 @default.
• W2095996735 cites W2153587608 @default.
• W2095996735 cites W2156280702 @default.
• W2095996735 cites W3133521311 @default.
• W2095996735 doi "https://doi.org/10.1016/j.nutres.2014.10.004" @default.
• W2095996735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25453543" @default.
• W2095996735 hasPublicationYear "2014" @default.
• W2095996735 type Work @default.
• W2095996735 sameAs 2095996735 @default.
• W2095996735 citedByCount "25" @default.
• W2095996735 countsByYear W20959967352015 @default.
• W2095996735 countsByYear W20959967352016 @default.
• W2095996735 countsByYear W20959967352017 @default.
• W2095996735 countsByYear W20959967352018 @default.
• W2095996735 countsByYear W20959967352019 @default.
• W2095996735 countsByYear W20959967352020 @default.
• W2095996735 countsByYear W20959967352021 @default.
• W2095996735 countsByYear W20959967352022 @default.
• W2095996735 crossrefType "journal-article" @default.
• W2095996735 hasAuthorship W2095996735A5003542900 @default.
• W2095996735 hasAuthorship W2095996735A5016369696 @default.
• W2095996735 hasAuthorship W2095996735A5019685555 @default.
• W2095996735 hasAuthorship W2095996735A5055675142 @default.
• W2095996735 hasAuthorship W2095996735A5058070060 @default.
• W2095996735 hasAuthorship W2095996735A5078643287 @default.
• W2095996735 hasAuthorship W2095996735A5080470851 @default.
• W2095996735 hasConcept C126322002 @default.
• W2095996735 hasConcept C134018914 @default.
• W2095996735 hasConcept C17991360 @default.
• W2095996735 hasConcept C204232928 @default.
• W2095996735 hasConcept C2776460901 @default.
• W2095996735 hasConcept C2776914184 @default.
• W2095996735 hasConcept C2777391703 @default.
• W2095996735 hasConcept C2778764654 @default.
• W2095996735 hasConcept C2779306644 @default.
• W2095996735 hasConcept C71924100 @default.

• next