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• W2096064497 abstract "Accumulation of 14C-labeled 1,3,6,8-tetrachlorodibenzo-p-dioxin (TCDD) and octachlorodibenzo-p-dioxin (OCDD) from water by rainbow trout fry (Salmo gairdneri) and fathead minnows (Pimephales promelas) was studied using a 5-d uptake and 24 to 48-d depuration period. Average exposure concentrations ranged from 4 to 211 ng/L for 1,3,6,8-TCDD and from 9 to 415 ng/L for OCDD. Equilibrium bioconcentration factors for total 14C in fish, calculated by use of a two-compartment first-order rate model, were 2,100 and 5,702 for 1,3,6,8-TCDD in trout fry and minnows, respectively, and 85 and 2,226 for OCDD in the same species. Elimination rates of both isomers were rapid, with half-lives of 14C ranging from 6 to 9 d for 1,3,6,8-TCDD and from 5 to 13 d for OCDD. The highest concentrations of radiolabeled 1,3,6,8-TCDD and OCDD were found in bile. A metabolite of 1,3,6,8-TCDD in bile was identified as a conjugate of a hydroxylated tetrachloro-derivative. Dietary exposure of rainbow trout resulted in low accumulation factors, ranging from 0.034 for OCDD to 0.018 for 1,3,6,8-TCDD, based on toluene-extractable radioactivity." @default.
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• W2096064497 date "1986-03-01" @default.
• W2096064497 modified "2023-10-12" @default.
• W2096064497 title "Bioconcentration and disposition of 1,3,6,8-tetrachlorodibenzo-<i>p</i>-dioxin and octachlorodibenzo-<i>p</i>-dioxin by rainbow trout and fathead minnows" @default.
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• W2096064497 doi "https://doi.org/10.1002/etc.5620050305" @default.
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