Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096068912> ?p ?o ?g. }
- W2096068912 endingPage "1775" @default.
- W2096068912 startingPage "1770" @default.
- W2096068912 abstract "The gastrointestinal tract (GIT) is affected in up to 90% of patients with SSc to a variable extent and severity. We aimed to establish the frequency and range of gastrointestinal (GI) symptoms in SSc patients at the Royal Free Hospital, a tertiary referral centre.A 52-item, previously validated, questionnaire capturing SSc-related gut dysfunction was given to consecutive patients with SSc attending the rheumatology outpatient department. The questionnaire assesses the 'frequency' of five categories of symptoms and their 'impact' on social functioning and emotional well-being. Patients' notes were reviewed to establish disease subtype, autoantibody profile and other internal organ involvement.We collected 402 completed questionnaires (357 females; mean age 55). Sixty-nine per cent of patients had lcSSc and 30% dcSSc with mean disease duration of 11 years. Mean questionnaire scores showed that patients have a wide range of GI symptoms. Ninety-four per cent of patients reported upper and 79% lower GI symptoms, 3% of patients reported no symptoms and 10% reported daily symptoms. There was no association between disease subtype or autoantibody profile and GI symptoms. There was a positive correlation between diarrhoea scores (high scores = best health) and pulmonary fibrosis (r = 0.134, P = 0.0068). No other association between GI symptoms and other internal organ involvement was found.GI symptoms, both upper and lower, are common in patients with SSc. Patients should be asked specifically about GI symptoms as they may be under-reported and therefore under-treated. GI focused questionnaire is an effective way to assess gut symptoms and adjust treatment." @default.
- W2096068912 created "2016-06-24" @default.
- W2096068912 creator A5008098676 @default.
- W2096068912 creator A5028255034 @default.
- W2096068912 creator A5038221938 @default.
- W2096068912 creator A5069032977 @default.
- W2096068912 creator A5070556531 @default.
- W2096068912 creator A5081188897 @default.
- W2096068912 date "2010-06-08" @default.
- W2096068912 modified "2023-10-18" @default.
- W2096068912 title "Assessment of gastrointestinal symptoms in patients with systemic sclerosis in a UK tertiary referral centre" @default.
- W2096068912 cites W1939859220 @default.
- W2096068912 cites W1964120739 @default.
- W2096068912 cites W1972485848 @default.
- W2096068912 cites W1972841810 @default.
- W2096068912 cites W1981355961 @default.
- W2096068912 cites W1983443397 @default.
- W2096068912 cites W1986260907 @default.
- W2096068912 cites W1996561912 @default.
- W2096068912 cites W2013117232 @default.
- W2096068912 cites W2019728745 @default.
- W2096068912 cites W2021619409 @default.
- W2096068912 cites W2039039771 @default.
- W2096068912 cites W2055112649 @default.
- W2096068912 cites W2061364794 @default.
- W2096068912 cites W2062948048 @default.
- W2096068912 cites W2074201320 @default.
- W2096068912 cites W2086326784 @default.
- W2096068912 cites W2091228452 @default.
- W2096068912 cites W2103494062 @default.
- W2096068912 cites W2118176317 @default.
- W2096068912 cites W2120317399 @default.
- W2096068912 cites W2121599003 @default.
- W2096068912 cites W2121758465 @default.
- W2096068912 cites W2126175558 @default.
- W2096068912 cites W2131014787 @default.
- W2096068912 cites W2137071299 @default.
- W2096068912 cites W2153802114 @default.
- W2096068912 cites W2169700106 @default.
- W2096068912 doi "https://doi.org/10.1093/rheumatology/keq147" @default.
- W2096068912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20530510" @default.
- W2096068912 hasPublicationYear "2010" @default.
- W2096068912 type Work @default.
- W2096068912 sameAs 2096068912 @default.
- W2096068912 citedByCount "91" @default.
- W2096068912 countsByYear W20960689122012 @default.
- W2096068912 countsByYear W20960689122013 @default.
- W2096068912 countsByYear W20960689122014 @default.
- W2096068912 countsByYear W20960689122015 @default.
- W2096068912 countsByYear W20960689122016 @default.
- W2096068912 countsByYear W20960689122017 @default.
- W2096068912 countsByYear W20960689122018 @default.
- W2096068912 countsByYear W20960689122019 @default.
- W2096068912 countsByYear W20960689122020 @default.
- W2096068912 countsByYear W20960689122021 @default.
- W2096068912 countsByYear W20960689122022 @default.
- W2096068912 countsByYear W20960689122023 @default.
- W2096068912 crossrefType "journal-article" @default.
- W2096068912 hasAuthorship W2096068912A5008098676 @default.
- W2096068912 hasAuthorship W2096068912A5028255034 @default.
- W2096068912 hasAuthorship W2096068912A5038221938 @default.
- W2096068912 hasAuthorship W2096068912A5069032977 @default.
- W2096068912 hasAuthorship W2096068912A5070556531 @default.
- W2096068912 hasAuthorship W2096068912A5081188897 @default.
- W2096068912 hasBestOaLocation W20960689121 @default.
- W2096068912 hasConcept C126322002 @default.
- W2096068912 hasConcept C159654299 @default.
- W2096068912 hasConcept C163764329 @default.
- W2096068912 hasConcept C1862650 @default.
- W2096068912 hasConcept C198451711 @default.
- W2096068912 hasConcept C203014093 @default.
- W2096068912 hasConcept C2776135927 @default.
- W2096068912 hasConcept C2779134260 @default.
- W2096068912 hasConcept C3020110884 @default.
- W2096068912 hasConcept C512399662 @default.
- W2096068912 hasConcept C71924100 @default.
- W2096068912 hasConcept C90924648 @default.
- W2096068912 hasConceptScore W2096068912C126322002 @default.
- W2096068912 hasConceptScore W2096068912C159654299 @default.
- W2096068912 hasConceptScore W2096068912C163764329 @default.
- W2096068912 hasConceptScore W2096068912C1862650 @default.
- W2096068912 hasConceptScore W2096068912C198451711 @default.
- W2096068912 hasConceptScore W2096068912C203014093 @default.
- W2096068912 hasConceptScore W2096068912C2776135927 @default.
- W2096068912 hasConceptScore W2096068912C2779134260 @default.
- W2096068912 hasConceptScore W2096068912C3020110884 @default.
- W2096068912 hasConceptScore W2096068912C512399662 @default.
- W2096068912 hasConceptScore W2096068912C71924100 @default.
- W2096068912 hasConceptScore W2096068912C90924648 @default.
- W2096068912 hasIssue "9" @default.
- W2096068912 hasLocation W20960689121 @default.
- W2096068912 hasLocation W20960689122 @default.
- W2096068912 hasOpenAccess W2096068912 @default.
- W2096068912 hasPrimaryLocation W20960689121 @default.
- W2096068912 hasRelatedWork W1596297887 @default.
- W2096068912 hasRelatedWork W1701437009 @default.
- W2096068912 hasRelatedWork W2006403424 @default.
- W2096068912 hasRelatedWork W2009701026 @default.