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• W2096151908 endingPage "40" @default.
• W2096151908 startingPage "27" @default.
• W2096151908 abstract "The purpose of the study was to determine which stressor qualities (escapable vs. inescapable stress and unconditioned vs. conditioned stress) can potentiate fear in the elevated plus-maze. While inescapable stress potentiated fear, escapable stress did not, but escapable stress increased the locomotor activity (closed arm entries). Inescapable stress only potentiated fear when re-exposure to the former shock compartment, 24 h after footshock and without further footshock, took place just before to 90 min before testing in the elevated plus-maze. We conclude that fear-potentiation in the plus-maze depends on stressor controllability and contextual conditioning. Fear-potentiation was reduced by the anxiolytic diazepam (0.5, 1.0 and 2.0 mg/kg, s.c.) and was further enhanced by the anxiogenic DMCM (1.0 mg/kg, s.c). The fear-potentiated plus-maze test may be a valuable tool in the search for novel anxiolytics and in the study of the neurobiology of fear-potentiation, fear conditioning and generalization of fear." @default.
• W2096151908 created "2016-06-24" @default.
• W2096151908 creator A5004200655 @default.
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• W2096151908 date "1999-01-01" @default.
• W2096151908 modified "2023-10-18" @default.
• W2096151908 title "Fear-Potentiation in the Elevated Plus-Maze Test Depends on Stressor Controllability and Fear Conditioning" @default.
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• W2096151908 doi "https://doi.org/10.3109/10253899909001110" @default.
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