FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096286871> ?p ?o ?g. }

• W2096286871 endingPage "192" @default.
• W2096286871 startingPage "185" @default.
• W2096286871 abstract "The metamorphosis of anuran amphibians is induced by thyroid hormone (TH). To study the molecular mechanisms underlying tail regression during metamorphosis, we established a cell line, XL-B4, from a Xenopus laevis tadpole tail at a premetamorphic stage. The cells expressed myoblast markers and differentiated into myotubes in differentiation medium. XL-B4 cells expressing fluorescent proteins were transplanted into tadpole tails. At 5 days post-transplantation, fluorescence was observed in myotube-like structures, indicating that the myoblastic cells could contribute to skeletal muscle. Exposure of XL-B4 cells to the TH triiodothyronine (T3) for several days significantly induced apoptotic cell death. We then examined an early response of expression of genes involved in apoptosis or myogenesis to T3. Treatment of the cells with T3 increased transcription of genes for matrix metalloproteinase-9 (MMP-9) and thyroid hormone receptor beta. Interestingly, the T3-treatment also increased myoD transcripts, but decreased the amounts of myogenin mRNA and myosin heavy chain. Importantly, we also observed upregulation of myoD expression and downregulation of myogenin expression in tails, but not in hind limbs, when tadpoles at a premetamorphic stage were treated with T3 for 1 day. These results indicated that T3 could not only induce apoptosis, but also attenuate myogenesis in tadpole tails during metamorphosis." @default.
• W2096286871 created "2016-06-24" @default.
• W2096286871 creator A5023153883 @default.
• W2096286871 creator A5033770267 @default.
• W2096286871 creator A5035849047 @default.
• W2096286871 creator A5043294176 @default.
• W2096286871 creator A5043563925 @default.
• W2096286871 creator A5063780889 @default.
• W2096286871 date "2015-06-01" @default.
• W2096286871 modified "2023-10-14" @default.
• W2096286871 title "Apoptosis and differentiation of Xenopus tail-derived myoblasts by thyroid hormone" @default.
• W2096286871 cites W1546664552 @default.
• W2096286871 cites W1964092051 @default.
• W2096286871 cites W1966023569 @default.
• W2096286871 cites W1969290780 @default.
• W2096286871 cites W1969726580 @default.
• W2096286871 cites W1971080289 @default.
• W2096286871 cites W1975979895 @default.
• W2096286871 cites W1977672570 @default.
• W2096286871 cites W1986367753 @default.
• W2096286871 cites W1996476805 @default.
• W2096286871 cites W2002503549 @default.
• W2096286871 cites W2003867300 @default.
• W2096286871 cites W2005500006 @default.
• W2096286871 cites W2007070249 @default.
• W2096286871 cites W2026418788 @default.
• W2096286871 cites W2037544680 @default.
• W2096286871 cites W2046548473 @default.
• W2096286871 cites W2053532994 @default.
• W2096286871 cites W2077504048 @default.
• W2096286871 cites W2083403745 @default.
• W2096286871 cites W2103770980 @default.
• W2096286871 cites W2112343474 @default.
• W2096286871 cites W2130595231 @default.
• W2096286871 cites W2134067617 @default.
• W2096286871 cites W2135662322 @default.
• W2096286871 cites W2146627558 @default.
• W2096286871 cites W2154405295 @default.
• W2096286871 doi "https://doi.org/10.1530/jme-14-0327" @default.
• W2096286871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25791374" @default.
• W2096286871 hasPublicationYear "2015" @default.
• W2096286871 type Work @default.
• W2096286871 sameAs 2096286871 @default.
• W2096286871 citedByCount "11" @default.
• W2096286871 countsByYear W20962868712016 @default.
• W2096286871 countsByYear W20962868712017 @default.
• W2096286871 countsByYear W20962868712019 @default.
• W2096286871 countsByYear W20962868712021 @default.
• W2096286871 countsByYear W20962868712022 @default.
• W2096286871 countsByYear W20962868712023 @default.
• W2096286871 crossrefType "journal-article" @default.
• W2096286871 hasAuthorship W2096286871A5023153883 @default.
• W2096286871 hasAuthorship W2096286871A5033770267 @default.
• W2096286871 hasAuthorship W2096286871A5035849047 @default.
• W2096286871 hasAuthorship W2096286871A5043294176 @default.
• W2096286871 hasAuthorship W2096286871A5043563925 @default.
• W2096286871 hasAuthorship W2096286871A5063780889 @default.
• W2096286871 hasBestOaLocation W20962868711 @default.
• W2096286871 hasConcept C104317684 @default.
• W2096286871 hasConcept C109115496 @default.
• W2096286871 hasConcept C126322002 @default.
• W2096286871 hasConcept C127561419 @default.
• W2096286871 hasConcept C134018914 @default.
• W2096286871 hasConcept C136397037 @default.
• W2096286871 hasConcept C148738053 @default.
• W2096286871 hasConcept C173758957 @default.
• W2096286871 hasConcept C190283241 @default.
• W2096286871 hasConcept C207200792 @default.
• W2096286871 hasConcept C2778106681 @default.
• W2096286871 hasConcept C2778288131 @default.
• W2096286871 hasConcept C3763915 @default.
• W2096286871 hasConcept C526584372 @default.
• W2096286871 hasConcept C55493867 @default.
• W2096286871 hasConcept C59822182 @default.
• W2096286871 hasConcept C6997183 @default.
• W2096286871 hasConcept C71924100 @default.
• W2096286871 hasConcept C86803240 @default.
• W2096286871 hasConcept C95444343 @default.
• W2096286871 hasConcept C97816823 @default.
• W2096286871 hasConceptScore W2096286871C104317684 @default.
• W2096286871 hasConceptScore W2096286871C109115496 @default.
• W2096286871 hasConceptScore W2096286871C126322002 @default.
• W2096286871 hasConceptScore W2096286871C127561419 @default.
• W2096286871 hasConceptScore W2096286871C134018914 @default.
• W2096286871 hasConceptScore W2096286871C136397037 @default.
• W2096286871 hasConceptScore W2096286871C148738053 @default.
• W2096286871 hasConceptScore W2096286871C173758957 @default.
• W2096286871 hasConceptScore W2096286871C190283241 @default.
• W2096286871 hasConceptScore W2096286871C207200792 @default.
• W2096286871 hasConceptScore W2096286871C2778106681 @default.
• W2096286871 hasConceptScore W2096286871C2778288131 @default.
• W2096286871 hasConceptScore W2096286871C3763915 @default.
• W2096286871 hasConceptScore W2096286871C526584372 @default.
• W2096286871 hasConceptScore W2096286871C55493867 @default.
• W2096286871 hasConceptScore W2096286871C59822182 @default.
• W2096286871 hasConceptScore W2096286871C6997183 @default.
• W2096286871 hasConceptScore W2096286871C71924100 @default.
• W2096286871 hasConceptScore W2096286871C86803240 @default.

• next