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- W2096291255 endingPage "1194" @default.
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- W2096291255 abstract "The ends of eukaryotic chromosomes are complex DNA structures called telomeres. The main function of a telomere is to provide a stable DNA terminus that is fully replicatable. The details of telomere structure and function are as yet unknown, largely because of the difficulty of cloning a protected DNA end. It has recently been shown that the ends of the Tetrahymena linear rDNA plasmid will function as telomeres on linear plasmids in yeast (Szostak and Blackburn 1982). Linear molecules with two Tetrahymena rDNA ends were constructed in vitro; these molecules were able to replicate in yeast, where they were maintained in a linear form. These linear plasmids were used to clone yeast telomeres, which appear to have several structural similarities to Tetrahymena telomeres." @default.
- W2096291255 created "2016-06-24" @default.
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- W2096291255 date "1983-01-01" @default.
- W2096291255 modified "2023-10-17" @default.
- W2096291255 title "Replication and Resolution of Telomeres in Yeast" @default.
- W2096291255 doi "https://doi.org/10.1101/sqb.1983.047.01.134" @default.
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