FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096322891> ?p ?o ?g. }

• W2096322891 endingPage "975" @default.
• W2096322891 startingPage "969" @default.
• W2096322891 abstract "19F solid-state nuclear magnetic resonance (NMR) was investigated as an analytical technique to quantify the amorphous phase in a fluorine-containing pharmaceutical candidate. The crystallinity of Compound 1 was calculated using two 19F T1 relaxation-based methods. The first method employs both the pure amorphous and the crystalline reference standards while the second method is model independent and utilizes a single standard. The 19F solid-state NMR results were confirmed with powder X-ray diffraction methods. From X-ray diffraction data, two linear calibration curves were obtained from blends of crystalline and amorphous Compound 1: one is based on the total integrated intensity of selected diffraction peaks and the other on the total intensity of the amorphous halo at 2θ positions that have no interference from crystalline diffraction peaks. The crystallinity of Compound 1 after compaction calculated by both 19F solid-state NMR methods was in excellent agreement with the results from the X-ray calibration curves. 19F solid-state NMR was shown to be a powerful technique in determining the amount of amorphous phase present in a pharmaceutical solid." @default.
• W2096322891 created "2016-06-24" @default.
• W2096322891 creator A5045683476 @default.
• W2096322891 creator A5058330415 @default.
• W2096322891 creator A5067799684 @default.
• W2096322891 creator A5072930460 @default.
• W2096322891 creator A5087315481 @default.
• W2096322891 date "2009-05-19" @default.
• W2096322891 modified "2023-10-15" @default.
• W2096322891 title "Quantification of compaction-induced crystallinity reduction of a pharmaceutical solid using¹⁹F solid-state NMR and powder X-ray diffraction" @default.
• W2096322891 cites W1983319174 @default.
• W2096322891 cites W1986769022 @default.
• W2096322891 cites W1994893251 @default.
• W2096322891 cites W2011502589 @default.
• W2096322891 cites W2018156260 @default.
• W2096322891 cites W2035065700 @default.
• W2096322891 cites W2035262666 @default.
• W2096322891 cites W2041315714 @default.
• W2096322891 cites W2044958545 @default.
• W2096322891 cites W2054466744 @default.
• W2096322891 cites W2055530178 @default.
• W2096322891 cites W2075179133 @default.
• W2096322891 cites W2079552263 @default.
• W2096322891 cites W2082076695 @default.
• W2096322891 cites W2082203116 @default.
• W2096322891 cites W2154804998 @default.
• W2096322891 cites W2335248207 @default.
• W2096322891 doi "https://doi.org/10.1080/03639040902729424" @default.
• W2096322891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19360510" @default.
• W2096322891 hasPublicationYear "2009" @default.
• W2096322891 type Work @default.
• W2096322891 sameAs 2096322891 @default.
• W2096322891 citedByCount "18" @default.
• W2096322891 countsByYear W20963228912013 @default.
• W2096322891 countsByYear W20963228912014 @default.
• W2096322891 countsByYear W20963228912015 @default.
• W2096322891 countsByYear W20963228912016 @default.
• W2096322891 countsByYear W20963228912017 @default.
• W2096322891 countsByYear W20963228912018 @default.
• W2096322891 countsByYear W20963228912019 @default.
• W2096322891 countsByYear W20963228912020 @default.
• W2096322891 countsByYear W20963228912021 @default.
• W2096322891 countsByYear W20963228912022 @default.
• W2096322891 countsByYear W20963228912023 @default.
• W2096322891 crossrefType "journal-article" @default.
• W2096322891 hasAuthorship W2096322891A5045683476 @default.
• W2096322891 hasAuthorship W2096322891A5058330415 @default.
• W2096322891 hasAuthorship W2096322891A5067799684 @default.
• W2096322891 hasAuthorship W2096322891A5072930460 @default.
• W2096322891 hasAuthorship W2096322891A5087315481 @default.
• W2096322891 hasConcept C113196181 @default.
• W2096322891 hasConcept C119128265 @default.
• W2096322891 hasConcept C120665830 @default.
• W2096322891 hasConcept C121332964 @default.
• W2096322891 hasConcept C153202636 @default.
• W2096322891 hasConcept C178790620 @default.
• W2096322891 hasConcept C185039092 @default.
• W2096322891 hasConcept C185592680 @default.
• W2096322891 hasConcept C192562407 @default.
• W2096322891 hasConcept C207114421 @default.
• W2096322891 hasConcept C23531484 @default.
• W2096322891 hasConcept C43617362 @default.
• W2096322891 hasConcept C44280652 @default.
• W2096322891 hasConcept C46141821 @default.
• W2096322891 hasConcept C46275449 @default.
• W2096322891 hasConcept C50515024 @default.
• W2096322891 hasConcept C56052488 @default.
• W2096322891 hasConcept C8010536 @default.
• W2096322891 hasConceptScore W2096322891C113196181 @default.
• W2096322891 hasConceptScore W2096322891C119128265 @default.
• W2096322891 hasConceptScore W2096322891C120665830 @default.
• W2096322891 hasConceptScore W2096322891C121332964 @default.
• W2096322891 hasConceptScore W2096322891C153202636 @default.
• W2096322891 hasConceptScore W2096322891C178790620 @default.
• W2096322891 hasConceptScore W2096322891C185039092 @default.
• W2096322891 hasConceptScore W2096322891C185592680 @default.
• W2096322891 hasConceptScore W2096322891C192562407 @default.
• W2096322891 hasConceptScore W2096322891C207114421 @default.
• W2096322891 hasConceptScore W2096322891C23531484 @default.
• W2096322891 hasConceptScore W2096322891C43617362 @default.
• W2096322891 hasConceptScore W2096322891C44280652 @default.
• W2096322891 hasConceptScore W2096322891C46141821 @default.
• W2096322891 hasConceptScore W2096322891C46275449 @default.
• W2096322891 hasConceptScore W2096322891C50515024 @default.
• W2096322891 hasConceptScore W2096322891C56052488 @default.
• W2096322891 hasConceptScore W2096322891C8010536 @default.
• W2096322891 hasIssue "8" @default.
• W2096322891 hasLocation W20963228911 @default.
• W2096322891 hasLocation W20963228912 @default.
• W2096322891 hasOpenAccess W2096322891 @default.
• W2096322891 hasPrimaryLocation W20963228911 @default.
• W2096322891 hasRelatedWork W1956143343 @default.
• W2096322891 hasRelatedWork W1977790219 @default.
• W2096322891 hasRelatedWork W1984854152 @default.
• W2096322891 hasRelatedWork W2066483243 @default.
• W2096322891 hasRelatedWork W2069218452 @default.
• W2096322891 hasRelatedWork W2133484783 @default.
• W2096322891 hasRelatedWork W2136694185 @default.

• next