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• W2096332502 abstract "Colonoscopy is considered the ‘gold standard’ for detecting colorectal neoplasia, and is increasingly viewed as a primary screening approach for these cancers [ [1] Rex D.K. Colonoscopy. Gastrointest Endosc Clin N Am. 2000; 10: 135-160 PubMed Google Scholar ]. However, it may fail to detect clinically important neoplastic lesions. Three large retrospective studies [ 2 Rex D.K. Rahmani E.Y. Haseman J.H. Lemmel G.T. Kaster S. Buckley J.S. et al. Relative sensitivity of colonoscopy and barium enema for detection of colorectal cancer in clinical practice. Gastroenterology. 1997; 112: 17-23 Abstract Full Text PDF PubMed Scopus (513) Google Scholar , 3 Hosokawa O. Shirasaki S. Kaizaki Y. Hayashi H. Douden K. Hattori M. Invasive colorectal cancer detected up to 3 years after a colonoscopy negative for cancer. Endoscopy. 2003; 35: 506-510 Crossref PubMed Scopus (74) Google Scholar , 4 Leaper M. Johnston M.J. Barclay M. Dobbs B.R. Frizelle F.A. Reasons for failure to diagnose colorectal carcinoma at colonoscopy. Endoscopy. 2004; 36: 499-503 Crossref PubMed Scopus (129) Google Scholar ] and one population-based analysis [ [5] Bressler B. Paszat L.F. Vinden C. Li C. He J. Rabeneck L. Colonoscopic miss rates for right-sided colon cancer: a population-based analysis. Gastroenterology. 2004; 127: 452-456 Abstract Full Text Full Text PDF PubMed Scopus (283) Google Scholar ] consistently showed that in routine clinical practice, miss rates for colorectal cancer at colonoscopy range from 2 to 6%. In the National Polyp Study, experienced endoscopists failed to identify approximately 25% of patients with incidental adenomas [ [6] Winawer S.J. Zauber A.G. O’Brien M.J. Ho M.N. Gottlieb L. Sternberg S.S. et al. Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. N Engl J Med. 1993; 328: 901-906 Crossref PubMed Scopus (878) Google Scholar ]. In tandem colonoscopy studies, the pooled miss rate for polyps of any size was 22% [ [7] van Rijn J.C. Reitsma J.B. Stoker J. Bossuyt P.M. van Deventer S.J. Dekker E. Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol. 2006; 11: 343-350 Crossref Scopus (1014) Google Scholar ]. In addition, the sensitivity of this examination for colorectal tumors varies between centres and examiners, causing differences in the quality of performance [ [8] Haseman J.H. Lemmel G.T. Rahmani E.Y. Rex D.K. Failure of colonoscopy to detect colorectal cancer: evaluation of 47 cases in 20 hospitals. Gastrointest Endosc. 1997; 45: 451-455 Abstract Full Text Full Text PDF PubMed Scopus (159) Google Scholar ]." @default.
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• W2096332502 title "Colonoscopy: The positive and the negative" @default.
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